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吸入性甲氧氟烷的临床应用及研究进展
Clinical application and research progress of inhaled methoxyflurane
【摘要】 甲氧氟烷作为氟化烃类麻醉剂,在麻醉剂量下可能会导致肾功能损害等严重的不良反应,但其亚麻醉剂量下产生的镇痛作用安全性好,耐受性高,是短期急性镇痛的治疗选择。本文从甲氧氟烷的药代动力学、临床有效性、不良反应及临床应用四方面进行叙述,探讨了甲氧氟烷作为镇痛剂在临床应用的可及性。甲氧氟烷作为吸入性镇痛剂使用方便,无需通过静脉给药即可为患者提供紧急镇痛,是门急诊紧急镇痛的良好选择。
【Abstract】 As a fluorinated hydrocarbon anesthetic, methoxyflurane may cause serious adverse reactions such as renal damage under anesthetic doses, but its analgesic effect at sub-anaesthetic doses is safe, high tolerability, and short-term acute Good choice for analgesia. This article describes the pharmacokinetics, clinical validity, adverse reactions and clinical application of methoxyflurane, and explores the feasibility of methoxyflurane as an analgesic in clinical application. Methoxyflurane is convenient to use as an inhaled analgesic. It can provide patients with emergency analgesia without intravenous administration. It is a good choice for emergency analgesia in pre-hospital and emergency settings.
- 【文献出处】 中国临床药理学与治疗学 ,Chinese Journal of Clinical Pharmacology and Therapeutics , 编辑部邮箱 ,2022年07期
- 【分类号】R614
- 【下载频次】46