【摘要】 目的 分析内固定术联合椎体成形术在脊柱骨折患者中的应用效果。方法 选择我院2017年6月至2020年6月收治的160例脊柱骨折患者为研究对象，随机将其分为对照组和观察组，各80例。对照组给予内固定术治疗，观察组给予内固定术联合椎体成形术治疗。比较两组患者的治疗优良率、手术指标、影像学参数、神经功能及脊柱功能。结果观察组的治疗优良率显著高于对照组，差异具有统计学意义（P<0.05）。观察组的手术时间显著长于对照组，术中失血量与术后引流量显著少于对照组，住院时间显著短于对照组，差异具有统计学意义（P<0.05）。术前，两组患者的椎体前缘与后缘高度压缩率、Cobb’s角、椎管侵占率及矢状面指数比较，差异不具有统计学意义（P>0.05）；术后3个月，两组的椎体前缘与后缘高度压缩率、椎管侵占率均显著降低，Cobb’s角均显著减小，矢状面指数均显著增加，且观察组显著优于对照组，差异具有统计学意义（P<0.05）。术后3个月，观察组的Frankel分级E级患者占比显著高于对照组，差异具有统计学意义（P<0.05）。术前，两组患者的ODI、Prolo评分比较，差异不具有统计学意义（P>0.05）；术后3个月，两组的ODI评分显著降低，Prolo评分显著升高，且观察组显著优于对照组，差异具有统计学意义（P<0.05）。结论 内固定术联合椎体成形术应用于脊柱骨折患者中可显著提升治疗效果，减少术中失血量与术后引流量，缩短住院时间，改善影像学参数、神经功能及脊柱功能，值得临床推广与应用。更多还原

【Abstract】 Objective To analyze the application effect of internal fixation combined with vertebroplasty in patients with spinal fractures. Methods A total of 160 patients with spinal fractures treated in our hospital from June 2017 to June 2020were selected as the research objects and randomly divided into control group and observation group, with 80 cases in each group. The control group was treated with internal fixation, and the observation group was treated with internal fixation combined with vertebroplasty. The excellent and good rate of treatment, operation indexes, imaging parameters, neurological function and spinal function were compared between the two groups. Results The excellent and good rate of treatment in the observation group was significantly higher than that in the control group, and the difference was statistically significant(P <0.05). The operation time of the observation group was significantly longer than that of the control group, the intraoperative blood loss and postoperative drainage were significantly less than those of the control group, the length of hospital stay was significantly shorter than that of the control group, and the differences were statistically significant(P <0.05). Before operation, there were no significant differences in the height compression rate of anterior and posterior edge of vertebral body, Cobb’s angle, spinal canal invasion rate and sagittal index between the two groups(P >0.05); at three months after operation, the height compression rate of anterior and posterior edge of vertebral body and spinal canal invasion rate in the two groups decreased significantly, the Cobb’s angle reduced significantly, the sagittal index increased significantly, those in the observation group were significantly better than the control group, and the differences were statistically significant(P <0.05). At three months after operation, the proportion of patients with Frankel grade E in the observation group was significantly higher than that in the control group, and the difference was statistically significant(P<0.05). Before operation, there were no significant differences in the ODI and Prolo scores between the two groups(P>0.05);at three months after operation, the ODI score in the two groups decreased significantly and the Prolo score increased significantly, those in the observation group were significantly better than the control group, and the differences were statistically significant(P <0.05). Conclusion The internal fixation combined with vertebroplasty applied in patients with spinal fractures can significantly improve the treatment effect, reduce intraoperative blood loss and postoperative drainage,shorten the length of hospital stay, improve imaging parameters, neurological function and spinal function, which is worthy of clinical promotion and application.更多还原