【摘要】 目的 探讨CT灌注成像对高血压性脑出血（HICH）亚急性期血肿情况的评估作用及血肿点征与血肿增大的关联性。方法 选取80例HICH亚急性期患者为研究对象，依据出血量将其分为低出血组（5～30 mL,n=50）、中出血组（31～60 mL,n=30）。依据血肿增大的判定标准将患者分为血肿增大组（n=26）和血肿未增大组（n=54）。对所有患者实施CT灌注成像，比较不同情况下患者的CT灌注指标。结果 中出血组的BF、BV低于低出血组，SP高于低出血组，ATT长于低出血组（P<0.05）。所有患者患侧BF、BV低于健侧，SP高于健侧，ATT长于健侧（P<0.05）。亚急性期，血肿增大组的BF、BV低于入院诊断时和血肿未增大组，SP高于入院诊断时和血肿未增大组，ATT长于入院诊断时和血肿未增大组（P<0.05）。血肿点征阳性对于血肿增大的预测值为92.31%，血肿点征阴性对于血肿未增大的预测值为92.59%。结论CT灌注成像可用于评估HICH亚急性期患者的血肿情况，血肿点征阳性与血肿增大的关联性较强。更多还原

【Abstract】 Objective To investigate the evaluation role of CT perfusion imaging on hematoma in subacute stage of hypertensive intracerebral hemorrhage(HICH) and the correlation analysis between hematoma dot sign and hematoma enlargement. Methods Eighty patients in HICH subacute stage were selected as the research objects. According to the hematoma volume, the patients were divided into low bleeding group(5-30 mL, n=50) and medium bleeding group(31-60 mL, n =30). According to the criteria of hematoma enlargement, the patients were divided into hematoma enlargement group(n=26) and hematoma non-enlargement group(n=54). CT perfusion imaging was performed in all patients, and the CT perfusion indexes of patients under different conditions were compared. Results BF and BV in the medium bleeding group were lower than those in the low bleeding group, SP was higher than that in the low bleeding group, and ATT was longer than that in the low bleeding group(P<0.05). BF and BV in the affected side were lower than those in the healthy side, SP was higher than that in the healthy side, and ATT was longer than that in the healthy side(P<0.05). In subacute stage, BF and BV in the hematoma enlargement group were lower than those at the time of admission diagnosis and the hematoma non-enlargement group, SP was higher than that at the time of admission diagnosis and the hematoma non-enlargement group, and ATT was longer than that at the time of admission diagnosis and the hematoma non-enlargement group(P <0.05). The predictive value of positive hematoma dot sign for hematoma enlargement was 92.31%, and the predictive value of negative hematoma dot sign for hematoma non-enlargement was 92.59%. Conclusion CT perfusion imaging can be used to evaluate the hematoma of HICH patients in subacute stage. The correlation between positive hematoma point sign and hematoma enlargement is strong.更多还原