【摘要】 目的 评估在线红外定位系统（On-Line Infrared Positioning System,OPS）在鼻咽癌放射治疗中对摆位误差测量的准确性及借助其摆位对分次间摆位误差稳定性的影响。方法 选取2017年8月至2018年12月于我院接受放射治疗的鼻咽癌患者59例（A组），运用OPS和锥形束CT(Cone-Beam Computed Tomography,CBCT)测量入组患者的摆位误差，比较2种方法的测量结果，分析OPS对摆位误差测量的准确性；选取2019年2月至2020年11月于我院接受放射治疗的鼻咽癌患者48例（B组），入组患者借助OPS进行治疗摆位，通过CBCT对入组患者首次与第2次治疗摆位进行摆位误差测量，分析借助OPS摆位分次间摆位误差的稳定性。结果 运用CBCT与OPS对A组患者的平移及旋转误差测量结果比较均无统计学差异（P>0.05）；运用CBCT对B组患者摆位误差测量发现，平移误差主要集中在1.5 mm以内，旋转误差在1°以内；B组患者首次与第2次摆位的平移及旋转误差比较均无统计学差异（P>0.05）。结论 OPS不但能够准确测量出鼻咽癌患者的摆位误差，而且借助其摆位能够提高摆位重复性，值得临床推广应用。更多还原

【Abstract】 Objective To evaluate the accuracy of on-line infrared positioning System(OPS) in the measurement of setup error in radiotherapy for nasopharyngeal carcinoma and the effect of OPS on the stability of interfractional setup error.Methods A total of 59 nasopharyngeal carcinoma patients who received radiotherapy in our hospital from August 2017 to December 2018(group A) were selected. OPS and cone-beam computed tomography(CBCT) were used to measure the setup error of the patients in the group. The measurement results of the two methods were compared. The accuracy of OPS for setup error was analyzed.A total of 48 nasopharyngeal carcinoma patients who received radiotherapy in our hospital from February 2019 to November 2020(group B) were selected. The enrolled patients were set up with the help of OPS. CBCT was used to measure the setup error of the first and second treatment sets of the enrolled patients, and the stability of setup error between the placement grades with the help of OPS was analyzed. Results There was no statistically significant difference between CBCT and OPS in the measurement results of translation and rotation errors of group A(P>0.05). Using CBCT to measure the setup error of group B, it could be seen that the translation error was mainly within 1.5 mm and the rotation error was within 1°. There was no statistically significant difference in translation and rotation errors between the first and second setup in group B(P>0.05). Conclusion OPS can not only accurately measure the setup error of nasopharyngeal carcinoma patients, but also improve the setup repeatability with the help of its setup,which is worthy of clinical application.更多还原