【摘要】 目的 探究血管在频率、温度、压力等电外科血管闭合设备操作环境下的阻抗变化规律。方法 采用恒流源、恒温水浴锅、LCR测试仪等搭建血管阻抗规律测试系统，并对兔粗大血管在不同影响因素作用下的阻抗变化规律进行研究。结果 在26℃、电流频率200～950 kHz条件下，内直径（5.1±0.1）mm、长（40.0±0.5）mm的兔血管实部阻抗随频率增加而减少，虚部阻抗先减少而后增加，出现频率转折特性，当频率在350 kHz时虚部阻抗最小；在350 kHz高频电流刺激下，血管阻抗随温度升高先减少，54℃后阻抗开始增加，出现温度转折特性；血管阻抗随受夹压增大降低，随两端电压升高增加。结论 这一血管阻抗规律的初步发现，可为血管闭合设备关键技术实时阻抗反馈技术研究提供一定的理论和技术基础。更多还原

【Abstract】 Objective To explore the impedance changes of vessels in the operating environment of electrosurgical vascular closure equipment, such as frequency, temperature and pressure. Methods The constant current source, constant temperature water bath and LCR tester were used to establish the vascular impedance law test system, and then the impedance change law of rabbit thick and large blood vessels under the action of different influencing factors was studied. Results Under the condition of 26℃ and current frequency from 200 to 950 kHz, the vascular impedance of rabbits with an inner diameter of(5.1±0.1) mm and length of(40.0±0.5) mm decreases with frequency. The real part of the impedance decreased with the increase of frequency, and the imaginary part decreased first and then increased, showing a frequency transition characteristic. When the frequency was 350 kHz, the imaginary part impedance was the minimum. Under the stimulation of 350 kHz high frequency current, the vascular impedance first decreased with the increase of temperature, and then began to increase after 54℃, showing a temperature transition characteristic.Vascular impedance decreased with increasing clamping pressure and increased with increasing voltage. Conclusion The preliminary discovery of vascular impedance law can provide a theoretical and technical basis for the research of real-time impedance feedback technology, which is a key technology of vascular closure device development.更多还原