【摘要】 目的：探讨药物洗脱球囊在冠状动脉真性分叉病变中的应用效果。方法：选取2020年1月-2021年8月单县中心医院收治的75例冠状动脉真性分叉病变患者作为研究对象。根据随机数字表法将其分为对照组(37例)和观察组(38例)。两组均接受单支架介入术治疗，对照组给予普通球囊扩张，观察组给予药物洗脱球囊治疗。比较两组术前、术后6个月时冠脉造影结果，不良事件，术前、术后1周时生活质量。结果：术后6个月，观察组病变血管狭窄率低于对照组，分支血管管腔最小直径大于对照组(P<0.05)。术后6个月内，观察组不良事件发生率低于对照组(P<0.05)。术后1周时，观察组精神情感、社会功能、躯体疼痛、生理职能评分均高于对照组(P<0.05)。结论：冠状动脉真性分叉病变接受药物洗脱球囊治疗，可让病变分支血管得到更好的扩张，加大管腔最小直径，降低不良事件发生率，进而改善生活质量。更多还原

【Abstract】 Objective:To investigate the application effect of drug-eluting balloon in the true coronary artery bifurcation diseases.Method:From January 2020 to August 2021,75 patients with true coronary artery bifurcation diseases admitted to the Shan County Central Hospital were selected as the study subjects.They were divided into control group (37 cases) and observation group (38 cases) according to the random number table method.Both groups received single stent intervention operation treatment,the control group was given the ordinary balloon dilation,and the observation group was given the drug-eluting balloon treatment.The coronary angiography results before and 6 months after operation,adverse events,quality of life before and 1 week after operation were compared between the two groups.Result:At 6 months after operation,the diseased vessel stenosis rate of observation group was lower than that of control group,and the minimum diameter of branch vessel lumen was greater than that of control group (P<0.05).Within 6 months after operation,the incidence of adverse events in the observation group was lower than that in the control group (P<0.05).At 1 week after operation,the scores of mental emotion,social function,physical pain and physiological function in the observation group were higher than those in the control group (P<0.05).Conclusion:The treatment of true coronary artery bifurcation disease with drug-eluting balloon can better expand the branch vessels of the disease,increase the minimum diameter of the lumen,reduce the incidence of adverse events,and improve the quality of life.更多还原