【摘要】 目的：观察磁共振钆塞酸二钠增强扫描与肝癌患者病理学分级、肝功能分级的相关性。方法：回顾性选取2017年1月-2021年9月江门市人民医院收治的肝癌患者为肝病组(50例)，另以同期体检的健康人群为对照组(20例)。两组均进行磁共振平扫及钆塞酸二钠增强扫描，采集肝脏相对强化程度(RE)。比较对照组及不同病理学分级、不同肝功能分级患者的磁共振RE值，采用Spearman秩相关分析病理学分级及肝功能分级与磁共振RE值的相关性。结果：对照组及不同肝功能分级患者磁共振RE值比较差异有统计学意义(F=26.871，P=0.000)。肝功能C级患者磁共振RE值低于对照组、肝功能A级和肝功能B级患者(P<0.05)；肝功能B级患者磁共振RE值低于对照组、肝功能A级患者；肝功能A级磁共振RE值低于对照组(P<0.05)。对照组及不同病理学分级患者磁共振RE值比较差异有统计学意义(F=33.681，P=0.000)。病理Ⅲ级患者磁共振RE值低于对照组、病理Ⅰ级、Ⅱ级患者(P<0.05)；病理学Ⅱ级患者磁共振RE值低于对照组和病理学Ⅰ级患者(P<0.05)；病理学Ⅰ级患者磁共振RE值低于对照组(P<0.05)。Spearman秩相关性分析显示，病理学分级、肝功能分级均与磁共振RE值呈负相关(r=-0.834、-0.882，P=0.010、0.009)。结论：磁共振钆塞酸二钠增强扫描信号强度与肝癌患者病理学分级、肝功能分级具有相关性，磁共振钆塞酸二钠增强扫描信号强度参数在评估肝癌患者病理学分级、肝功能分级中具有一定的临床价值。更多还原

【Abstract】 Objective:To observe the correlation of magnetic resonance enhanced scanning with Disodium Gadolinium Selenate and pathological grade and liver function grade of patients with liver cancer.Method:The patients with liver cancer treated in Jiangmen Municipal People’s Hospital from January 2017 to September 2021 were retrospectively selected as the liver disease group (50 cases),and the healthy people undergoing physical examination in the same period as the control group (20 cases).Both groups underwent magnetic resonance plain scan and enhanced scanning with Disodium Gadolinium Selenate,the relative enhancement degree (RE) of liver was collected.The magnetic resonance RE values of the control group and patients with different pathological grades and different liver function grades were compared.Spearman rank correlation was used to analyze the correlation between pathological grades,liver function grades and magnetic resonance RE values.Result:There was significant difference in magnetic resonance RE values between the control group and patients with different liver function grades (F=26.871,P=0.000).The magnetic resonance RE value of patients with liver function grade C was lower than that of the control group,patients with liver function grade A and patients with liver function grade B (P<0.05);the RE value of magnetic resonance in patients with grade B liver function was lower than that in control group and grade A liver function patients;the magnetic resonance RE value in grade A of liver function was lower than that of the control group (P<0.05).There was significant difference in magnetic resonance RE values between the control group and patients with different pathological grades (F=33.681,P=0.000).The RE value of magnetic resonance in pathological grade Ⅲ patients was lower than that in control group,pathological grade Ⅰ and Ⅱ patients (P<0.05);the RE value of magnetic resonance in pathological grade Ⅱ patients was lower than that in control group and pathological grade Ⅰ patients (P<0.05);the RE value of magnetic resonance in patients with pathological grade Ⅰ was lower than that in the control group (P<0.05).Spearman rank correlation analysis showed that pathological grade and liver function grade were negatively correlated with magnetic resonance RE values (r=-0.834,-0.882,P=0.010,0.009).Conclusion:The signal intensity of magnetic resonance enhanced scanning with Disodium Gadolinium Selenate is correlated with the pathological grade and liver function grade of patients with liver cancer.The signal intensity parameters of magnetic resonance enhanced scanning with Disodium Gadolinium Selenate have clinical value in evaluating the pathological grade and liver function grade of patients with liver cancer.更多还原