【摘要】 目的 了解医护人员对HIV暴露前和非职业HIV暴露后知晓情况及其提供服务情况。方法 2021年1—3月采用电子问卷的形式，收集成都、济南、南京、长沙和重庆市的5家艾滋病治疗定点医院医护人员的基本情况、艾滋病防治基础知识知晓、暴露前预防（PrEP）知识和暴露后预防（nPEP）知识知晓及其相关服务提供情况，采用SPSS 22.0软件进行统计学描述分析和Logistic回归分析，以P<0.05为差异有统计学意义。结果 共调查1 036名医护人员，平均年龄（35.9±8.5）岁。其中听说过PrEP和nPEP的分别有919人和987人。知晓PrEP和nPEP知识的分别占42.2%(388/919)和41.7%(412/987)。PrEP服务相关因素的单因素分析发现，年龄、性别、职业、PrEP和nPEP基础知识知晓情况与PrEP相关服务提供相关，差异有统计学意义（P<0.001）。多因素Logistic回归分析结果显示，女性、nPEP不知晓者提供PrEP服务的概率更低。n PEP服务相关因素的单因素分析结果显示，城市、年龄、性别、文化程度、职业、职称及PrEP和nPEP基础知识知晓情况对nPEP服务提供情况有影响。多因素Logistic回归结果显示，年龄小于31岁的医护人员提供nPEP服务的概率低于50岁以上的医护人员（a OR=2.572;95%CI:1.223～5.407）；护士（aOR=0.413;95%CI:0.264～0.646）、nPEP不知晓者（a OR=0.463;95%CI:0.338～0.635）提供nPEP服务的概率低于医生和nPEP知识知晓者。结论 艾滋病防治工作相关从业人员作为PrEP和nPEP相关服务的提供者，亟需继续加强其关于PrEP和nPEP知识和技能的培训。更多还原

【Abstract】 Objective To learn about the knowledge awareness of HIV pre-exposure prophylaxis(PrEP)and non-occupational post-exposure prophylaxis(nPEP) among medical staff and their service status.Methods From January to March 2021, an electronic questionnaire was used to collect the basic information, awareness of basic knowledge of HIV/AIDS prevention and treatment, awareness of PrEP and nPEP,and relevant service provision of medical staff from 5 designated hospitals for HIV/AIDS treatment in Chengdu, Jinan, Nanjing, Changsha and Chongqing. SPSS 22.0 software was used for statistical description analysis and logistic regression analysis. P<0.05 was considered as statistically significant. Results A total of 1 036 medical workers were surveyed. The average age was 35.9±8.5 years old. Among them,919 and 987 had heard of PrEP and nPEP,respectively. A total of 388(42.2%,388/919) and 412(41.7%,412/987) medical workers had knowledge of PrEP and nPEP,respectively. The result of univariate analysis of PrEP service-related factors showed that age, gender, occupation and the knowledge awareness of PrEP and nPEP were associated with PrEP service status. And the difference was statistically significant(P<0.001). Multivariate logistic regression analysis indicated that, women and those unaware of nPEP were less likely to offer PrEP. The result of univariate analysis of nPEP service-related factors showed that, city, age,gender,education background,occupation,professional qualifications,and the knowledge awareness of PrEP and n PEP were influencing factors of nPEP service status. Multivariate logistic regression analysis results showed that,the probability of providing nPEP service of medical workers less than31 years old was lower than that of those who were more than 50 years old(aOR(odds ratio) =2.572, 95% CI(confidence interval): 1.223-5.407). The probability of providing nPEP service of nurses(aOR=0.413; 95% CI: 0.264-0.646) and those who don’t know the nPEP(aOR=0.463;95% CI: 0.338-0.635) were lower than those of doctors and those with knowledge of nPEP.Conclusions There is an urgent need to continue strengthening the training of knowledge and skills of HIV PrEP and nPEP among HIV/AIDS prevention and treatment workers who were providers of PrEP and nPEP related services.更多还原