【摘要】 目的 探讨经皮椎体成形术治疗脊柱压缩性骨折的效果及对患者炎性因子水平的影响。方法 70例脊柱压缩性骨折患者随机分为两组各35例，对照组采用椎体后凸成形术治疗，观察组采用经皮椎体成形术治疗，比较两组的手术指标、疼痛程度及炎性因子水平。结果 观察组的手术时间短于对照组，术中出血量与骨水泥注入量均低于对照组，术后伤椎增加高度高于对照组，术后1 d、 3 d、 7 d的VAS评分均低于对照组，术后CRP、 PCT及IL-6水平均低于对照组（P <0.05）。结论 经皮椎体成形术治疗脊柱压缩性骨折的效果显著，可改善机体炎性状态，降低术后疼痛程度。更多还原

【Abstract】 Objective To explore the effect of percutaneous vertebroplasty in the treatment of spinal compression fracture and its impact on the levels of inflammatory factors of patients. Methods 70 patients with spinal compression fracture were randomly divided into two groups, with 35 cases in each group. The control group was treated with kyphoplasty of the vertebral body, and the observation group was treated with percutaneous vertebroplasty. The surgical indicators, pain degree and levels of inflammatory factors were compared between the two groups. Results The operation time in the observation group was shorter than that in the control group, the intraoperative blood loss amount and bone cement injection amount were lower than those in the control group, the increased height of injured vertebra after surgery was higher than that in the control group, the VAS scores at 1 d, 3 d and 7 d after surgery were lower than those in the control group, and the levels of CRP, PCT and IL-6 after surgery were lower than those in the control group(P <0.05). Conclusions Percutaneous vertebroplasty in the treatment of spinal compression fracture has significant effect, which can improve inflammatory state and reduce postoperative pain degree.更多还原