【摘要】 目的 了解乳腺癌患者新型冠状病毒肺炎(COVID-19)疫苗接种情况及疫苗犹豫的影响因素,为更好地解决乳腺癌患者特殊人群的相关问题提供依据。方法 2021年7月9-30日采用方便抽样的方法对重庆市各大三甲医院乳腺癌中心康复组织及微信群的500例乳腺癌患者进行一般资料问卷、COVID-19疫苗接种及疫苗犹豫现状量表的自评调查,采用SPSS22.0统计软件进行数据分析。结果 500例患者中完成有效问卷454份,已接种COVID-19疫苗90例,未接种COVID-19疫苗364例。将疫苗犹豫者、不愿意接种疫苗者、已接种疫苗但曾经接种意愿不坚定者归入疫苗犹豫组,共242例,疫苗犹豫率为53.30%。不同年龄、有无服用乳腺癌相关治疗药物、医师是否不建议注射COVID-19疫苗、不同患病时间乳腺癌患者疫苗犹豫率比较,差异均有统计学意义(P<0.05)。服用乳腺癌治疗药物患者疫苗犹豫是未服用乳腺癌治疗药物患者的1.28倍,医师不建议注射COVID-19疫苗患者疫苗犹豫是医师没有不建议注射COVID-19疫苗患者的1.57倍,患病3年内患者疫苗犹豫是患病3年后患者的2.49倍。结论 目前,乳腺癌患者疫苗接种率较低,应根据疫苗犹豫现状制定精细化接种方案。更多还原

【Abstract】 Objective To investigate the status of COVID-19 vaccination among breast cancer patients and the influencing factors of vaccine hesitancy,and to provide evidence for better addressing the issues related to the special population of breast cancer patients.Methods A total of 500 breast cancer patients were selected to adopt a convenient sampling method from the rehabilitation organization and We Chat group of the breast cancer center in tertiary A comprehensive treatment hospitals of Chongqing from July 9 to 30,2021.The patients’ general information,COVID-19 vaccination and vaccine hesitancy were self-assessed.SPSS22.0 was used for data analysis.Results A total of 454 valid questionnaires were completed,including 90 patients who had received the COVID-19 vaccine and 364 patients who had not.A total of 242 cases were included in the vaccine hesitation group,including those who were hesitant,unwilling to be vaccinated,and those who had been vaccinated but were not determined to be vaccinated.The vaccine hesitation rate was 53.30%.There were statistically significant differences in vaccine hesitancy rates among breast cancer patients of different ages,whether they had taken breast cancer-related drugs,whether doctors did not recommend the injection of COVID-19 vaccine,and different periods of illness(P<0.05).Logistic regression analysis showed that patients taking breast cancer treatment drugs were 1.28 times more hesitant to the vaccine than those not taking breast cancer treatment drugs.And 1.57 times as many patients were hesitant to get vaccinated against COVID-19 as those who were not.Breast cancer patients within 3 years were 2.49 times more likely to hesitate about vaccines than those after 3 years.Conclusion At present,the vaccine coverage rate of breast cancer patients is low,and a refined vaccination plan should be formulated according to the status of vaccine hesitancy.更多还原