【摘要】 衰老是心房颤动(房颤)的独立危险因素，但衰老参与房颤的细胞、分子机制仍不明确。衰老是一种生理性的变化，当机体处于病理状态下时会加剧衰老的过程，表现出异常生理状态，增加衰老相关疾病的发生。衰老会引起细胞形态及功能变化。现总结先前的研究成果，对衰老与房颤之间的关系进行总结，特别是对衰老导致的生理变化与房颤发生的关系进行讨论，了解衰老和房颤的内在联系，寻找衰老导致房颤发生的关键环节，从而寻找房颤的潜在治疗方法，为房颤的治疗带来新的选择。更多还原

【Abstract】 Aging is an independent risk factor for atrial fibrillation, but the cellular and molecular mechanisms of aging involved in atrial fibrillation are still unclear.Aging is a physiological change.When the body is in a pathological state, it will aggravate the process of aging, show abnormal physiological state, and increase the occurrence of aging-related diseases.Aging causes changes in cell morphology and function.In this paper, we summarize previous research results and discuss the relationship between aging and atrial fibrillation, especially the relationship between physiological changes caused by aging and the occurrence of atrial fibrillation, to understand the intrinsic connection between aging and atrial fibrillation, to find the key link between aging and the occurrence of atrial fibrillation, so as to find potential treatments for atrial fibrillation and bring new options for the treatment of atrial fibrillation.更多还原