【摘要】 目的 探讨舒芬太尼联合甲苯磺酸瑞马唑仑或丙泊酚在无痛人流中对患者苏醒后心理应激、躁动的影响。方法 选取2021年6月～2021年10月于本院接受无痛人流术患者100例，按随机数字表法分为两组，即对照组50例，采用舒芬太尼联合丙泊酚麻醉；观察组50例，采用舒芬太尼联合甲苯磺酸瑞马唑仑麻醉。比较两组麻醉注射后各时间点的心理应激指标、麻醉效果、给药后改良警觉/镇静(MOAA/S)评分≤3分时间、给药后2、4、6 min内MOAA/S评分、术后躁动发生率。正态计量资料以 t 检验；计数资料以 x~2 检验。结果 观察组麻醉后T1、T2时平均动脉压、心率、血氧饱和度显著高于对照组，焦虑指数(ANXi)显著低于对照组(P<0.05)；观察组意识消失时间、苏醒时间显著短于对照组，但给药后2、4 min内MOAA/S评分显著高于对照组(P<0.05)；观察组麻醉后躁动发生率(2.00%)显著低于对照组(20.00%)(P<0.05)。结论 较舒芬太尼联合丙泊酚麻醉方案相比，舒芬太尼联合甲苯磺酸瑞马唑仑麻醉方案可改善无痛人流中对患者苏醒后心理应激反应，减少躁动的发生。更多还原

【Abstract】 Objective To investigate the effect of sufentanil combined with remazolam tosylate or propofol on the psychological stress and agitation of patients after recovery during painless abortion.Methods A total of 100 patients who received painless abortion in our hospital from June to October 2021 were selected and divided into two groups according to the random number table method,namely the control group of 50 patients,who received sufentanil combined with propofol anesthesia;the observation group 50 cases were anesthetized with sufentanil combined with remazolam tosylate.The psychological stress index,anesthesia effect,post-administration modified alertness/sedation (MOAA/S) score ≤ 3 points,and MOAA/S score within 2,4,and 6 minutes after administration were compared between the two groups at each time point,the incidence of postoperative agitation.t test for normal measurement data;x~2 test for count data.Results The mean arterial pressure,heart rate and blood oxygen saturation of the observation group at T1 and T2 after anesthesia were significantly higher than those of the control group,and the anxiety index (ANXi) was significantly lower than that of the control group (P<0.05);the disappearance time and wake-up time of the observation group were significantly shorter than those of the control group,but the MOAA/S score within 2 and 4 minutes after administration was significantly higher than that of the control group (P<0.05);the incidence of agitation after anesthesia in the observation group (2.00%) was significantly lower than that in the control group (20.00%) (P<0.05).Conclusion Compared with sufentanil combined with propofol anesthesia program,sufentanil combined with remazolam tosylate anesthesia program can improve the psychological stress response of patients after recovery during painless abortion and reduce the occurrence ofagitation.更多还原