【摘要】 目的 研究12月龄高危儿早期发展干预后神经发育的不同结果。方法 将1246例高危儿按门诊单双号随机分成干预组(n=631)和对照组(n=615)，给予干预组早期发展干预，给予对照组常规干预。两组被试在满12月龄时使用Gesell发育诊断量表(Gesell)评估发育情况，采用 x~2 检验。结果 干预组正常数、可疑(边缘状态)数与对照组差异显著(P<0.05)；干预组多能区发育异常数与对照组差异显著(P<0.05)。结论 给予高危儿早期发展干预效果显著，能够显著降低可疑(边缘状态)率，改善多能区发育情况。更多还原

【Abstract】 Objective To study the different results of neurodevelopment in 12-month-old high-risk infants after early development intervention.Methods 1246 high-risk infants were divided into early promotion intervention group (n=631) and control group (n=615) according to the outpatient odd and even number.Early development intervention was given to the intervention group,and routine intervention was given to the control group.At the age of 12 months,the two groups of subjects used the Gesell developmental scales (Gesell) to assess their development,using the x~2 test.Results The normal number and suspicious (marginal state) numbers of the intervention group were significantly different from those of the control group (P<0.05);the number of pluripotent zone developmental abnormalities in the intervention group was significantly different from that of the control group (P<0.05).Conclusion Early development intervention for high-risk infants has a significant effect,which can significantly reduce the suspicious (marginal state) rate and improve the development of the pluripotent zone.更多还原