【摘要】 目的分析伴躯体症状对抑郁症患者的影响。方法 2020年3月～2021年5月,按照是否伴有躯体症状将65例抑郁症患者分为伴躯体症状组(n=43)、不伴躯体症状组(n=22)。在基线与干预4周后,采用认知功能缺陷自评问卷(PDQ-D)、席汉残疾量表(SDS)、汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD)对两组患者进行评估;比较两组临床有效率。两组PDQ-D、SDS、HAMA、HAMD数据采用t检验,临床有效率采用x2检验。分析PDQ-D、SDS、HAMA、HAMD评分与伴躯体症状的相关性(Pearson相关分析)。结果在基线与干预4周后,伴躯体症状组PDQ-D、SDS、HAMA、HAMD评分均高于不伴躯体症状组(P<0.05);干预4周后,伴躯体症状组临床有效率低于不伴躯体症状组(P<0.05)。基线、干预4周后,PDQ-D、SDS、HAMA、HAMD评分与伴躯体症状呈正相关。结论伴躯体症状的抑郁症患者疗效更差、焦虑抑郁更重、认知功能损害和社会功能损害更重;PDQ-D、SDS、HAMA、HAMD评分与伴躯体症状呈正相关。更多还原

【Abstract】 Objective To analyze the impact of physical symptoms on patients with depression. Methods From March 2020 to May 2021, 65 depression patients were divided into groups with physical symptoms(n=43) and groups without physical symptoms(n=22) according to whether they were accompanied by physical symptoms. After baseline and 4 weeks of intervention, the two groups of patients were treated with the perceived deficit questionnaire for depression(PDQ-D), Sheehan disability scale(SDS), Hamilton anxiety scale(HAMA), and Hamilton depression scale(HAMD);to compare the clinical effectiveness of the two groups. The data of PDQ-D, SDS, HAMA, and HAMD of the two groups adopts t test, and the clinical effective rate adopts x2 test. To analyze the correlation between PDQ-D, SDS, HAMA, HAMD scores and physical symptoms(Pearson correlation analysis). Results After baseline and 4 weeks of intervention, the PDQ-D, SDS, HAMA, and HAMD scores of the group with physical symptoms were higher than those of the group without physical symptoms(P<0.05); after 4 weeks of intervention, the clinical effective rate of the group with physical symptoms was low in the group without physical symptoms(P<0.05). After baseline and 4 weeks of intervention, PDQ-D, SDS, HAMA, and HAMD scores were positively correlated with accompanying physical symptoms. Conclusion Depression patients with physical symptoms have worse efficacy,anxiety and depression are more serious, cognitive impairment and social function impairment are more severe, PDQ-D, SDS, HAMA, HAMD scores are positively correlated with physical symptoms.更多还原