【摘要】 目的 探讨全身麻醉手术患者术后发生下肢深静脉血栓（DVT）的危险因素。方法 收集2021年1月至2022年6月北京积水潭医院收治的118例接受全身麻醉的手术患者的临床资料，根据术后住院期间是否发生下肢DVT将患者分为血栓组（n=27）和对照组（n=91）。分析全身麻醉患者术后住院期间发生下肢DVT的危险因素。结果 两组患者的年龄、收缩压、血糖、C反应蛋白（CRP）水平、手术类型、手术时间、术中低体温情况及术前D-二聚体水平升高情况比较，差异均有统计学意义（P<0.05）。两组患者的性别、体重指数、总胆固醇水平、甘油三酯水平、合并症情况、降钙素原（PCT）水平、白细胞（WBC）计数、中性粒细胞（NEU）计数、淋巴细胞（LYM）计数、血小板（PLT）计数、术中出血量及术中输血情况比较，差异均无统计学意义（P>0.05）。多因素分析结果显示，年龄≥65岁、术前CRP水平升高、术前D-二聚体水平升高及恶性肿瘤切除术均是全身麻醉患者术后住院期间发生下肢DVT的独立危险因素（P<0.05）。结论 年龄、术前CRP水平、术前D-二聚体水平、手术类型均与全身麻醉患者术后住院期间是否发生下肢DVT有关，术前应及时识别下肢DVT高危患者。更多还原

【Abstract】 Objective To investigate the risk factors of lower extremity deep vein thrombosis(DVT) after surgery in patients with general anesthesia. Method The clinical data of 118 surgical patients who underwent general anesthesia in Beijing Jishuitan Hospital from January 2021 to June 2022 were collected. Patients were divided into thrombosis group(n=27) and control group(n=91) according to whether lower extremity DVT occurred during postoperative hospitalization. The risk factors of lower extremity DVT during hospitalization after general anesthesia were also explored. Result There were statistically significant differences in age, systolic blood pressure, blood sugar, C reaction protein(CRP) level, operation type, operation time, intraoperative hypothermia,and preoperative D-dimer level between the two groups(P<0.05). The gender, body mass index, total cholesterol level, triglyceride level, comorbidities, procacitonin(PCT) level, white blood cell(WBC) count, neutrophil(NEU) count, lymphocyte(LYM) count, blood platelet(PLT) count, intraoperative blood loss, and intraoperative blood transfusion were compared between the two groups of patients, the differences were not statistically significant(P>0.05). The results of multivariate analysis showed that age ≥65 years old, elevated preoperative CRP levels, elevated preoperative D-dimer levels, and malignant tumors resection were independent risk factors for lower extremity DVT during postoperative hospitalization in patients with general anesthesia(P<0.05). Conclusion Age,preoperative CRP level, preoperative D-dimer level, and type of surgery are all related to the occurrence of lower extremity DVT after surgery in patients with general anesthesia. It is necessary to identify high-risk patients with lower extremity DVT before the surgery.更多还原