【摘要】 目的:比较子宫内膜异位症(EMs)不孕患者行体外受精/卵胞浆内单精子注射(IVF/ICSI)助孕治疗中选择全胚冷冻与鲜囊胚移植的妊娠结局及母婴并发症。方法:选取2014年1月1日至2018年12月31日在山东大学附属生殖医院接受IVF/ICSI治疗的EMs不孕患者，回顾分析活产率、临床妊娠率、累积妊娠率等妊娠结局及母婴并发症。结果:共纳入462例EMs不孕患者，校正混杂因素后，与移植鲜囊胚相比，全胚冷冻可获得较高的累积妊娠率(77.06%vs 61.04%)及较低的生化妊娠流产率(10.20%vs 24.63%)和妊娠期糖尿病(GDM)发生率(1.52%vs 7.20%),两组在其他妊娠结局及母婴并发症方面，差异无统计学意义(P>0.05)。结论:在EMs不孕患者中，全胚冷冻移植可获得较高的累积妊娠率及较低的GDM风险。更多还原

【Abstract】 Objective:To evaluate and compare in vitro fertilization/intracytoplasmic sperm injection(IVF/ICSI) outcomes using frozen-all blastocyst transfer and fresh blastocyst transfer in women with endometriosis infertility.Methods:Select infertility patients with endometriosis received IVF/ICSI treatment in Reproductive Hospital Affiliated to Shandong University from January 1,2014 to December 31,2018.The live birth rate, clinical pregnancy rate, cumulative pregnancy rate and maternal and neonatal complications were retrospectively analyzed.Results:A total of 462 women were included in this study, compared to fresh blastocyst transfer, frozen-all blastocyst transfer resulted in a higher cumulative pregnancy rate(77.06% vs 61.04%),and a lower biochemical pregnancy abortion rate(10.20% vs 24.63%),and gestational diabetes mellitus(GDM) rate(1.52% vs 7.20%).There were no significant differences between groups in other reproductive outcomes and maternal and neonatal complications.Conclusion:Among infertile women with endometriosis, frozen-all blastocyst transfer was associated with a higher cumulative pregnancy rate and a lower risk of GDM than that in fresh blastocyst transfer.更多还原