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山东省MSM暴露前预防知晓和使用情况及其影响因素
Awareness and use of pre-exposure prophylaxis and influencing factors among men who have sex with men in Shandong province
【摘要】 目的 了解山东省MSM对暴露前预防(PrEP)的知晓和使用情况,探讨其影响因素。方法 采用网络宣传和社会组织推荐相结合的方式招募研究对象,通过问卷星进行电子问卷调查。利用χ2检验、Logistic回归分析PrEP知晓、使用的影响因素,并用森林图进行结果可视化。结果 共纳入MSM 1 256人,PrEP知晓率为72.5%(910/1 256),使用率为8.4%(105/1 256)。多因素Logistic回归结果显示,与PrEP知晓相关的因素包括更高学历(OR=1.52,95%CI:1.06~2.17;OR=1.82,95%CI:1.30~2.54)、曾有固定性伴(OR=1.78,95%CI:1.23~2.58)、近6个月性伴数≥2个(OR=1.40,95%CI:1.05~1.86)、近6个月使用过新型毒品(OR=3.01,95%CI:1.72~5.28)、了解一些或非常了解我国MSM感染HIV的严重程度(OR=1.72,95%CI:1.09~2.74;OR=6.27,95%CI:2.62~14.99)、曾接受过有关预防艾滋病的服务(OR=2.08,95%CI:1.54~2.81)、在网络中接触过艾滋病相关讯息(OR=1.94,95%CI:1.28~2.94)、曾做过HIV检测(OR=2.23,95%CI:1.42~3.49)和知晓艾滋病相关知识(OR=3.27,95%CI:2.17~4.93)。与PrEP使用相关的因素包括农村户口(OR=0.60,95%CI:0.39~0.94)、近6个月与男性发生过“无保护肛交”(OR=0.51,95%CI:0.30~0.85)、近6个月有过多人男男性行为(OR=2.30,95%CI:1.36~3.88)、自我感知HIV感染风险较高(OR=4.69,95%CI:2.02~10.89)和PrEP知晓(OR=13.57,95%CI:4.21~43.76)。结论 山东省MSM的PrEP知晓率较高,使用率较低,二者之间存在巨大差异。应加强对MSM的PrEP宣传教育,增加MSM对PrEP的知晓及使用。
【Abstract】 Objective This study aimed to understand the awareness and use of pre-exposure prophylaxis(PrEP)among MSM in Shandong province. Its influencing factors were explored to provide a basis for improving the awareness and use of PrEP. Methods The participants were recruited through the combination of online publicity and MSM group’s recommendations. An electronic questionnaire survey was conducted through Sojump(an online survey platform). The influencing factors of PrEP awareness and use were analyzed by χ2test and logistic regression. Forest plots were used for the results visualization. Results A total of 1, 256 MSM in Shandong Province were included in this study. The awareness rate of PrEP among MSM was 72.5%(910/1256) and the use rate was 8.4%(105/1256). Factors associated with awareness of PrEP included higher educational level(OR=1.52, 95%CI: 1.06-2.17; OR=1.82, 95%CI: 1.30-2.54), having regular sexual partners(OR=1.78, 95%CI:1.23-2.58), having more than one sexual partners(OR=1.40, 95%CI:1.05-1.86)and used new chemicals(OR=3.01, 95%CI: 1.72-5.28) in recent 6 months, realizing the severity of HIV infection among MSM in China(OR=1.72, 95%CI:1.09-2.74; OR=6.27, 95%CI:2.62-14.99), receiving services related to the prevention of HIV(OR=2.08, 95%CI:1.54-2.81), contacting HIV related information on the Internet(OR=1.94, 95%CI:1.28-2.94), had HIV testing before(OR=2.23, 95%CI:1.42-3.49) and known HIV related knowledge(OR=3.27, 95%CI:2.17-4.93). Factors associated with the use of PrEP included come from village(OR=0.60, 95%CI:0.39-0.94), condomless anal sex(OR=0.51,95%CI: 0.30-0.85), group intercourse behavior(OR=2.30, 95%CI: 1.36-3.88) with men in recent 6 months,higher self-perception of HIV infection(OR=4.69,95%CI: 2.02-10.89) and PrEP awareness(OR=13.57,95%CI: 4.21-43.76). Conclusions The awareness rate of PrEP among MSM in Shandong province is relatively high, but the rate of use is low. There is a huge difference between PrEP awareness and actual use. We should strengthen the education of PrEP among MSM to increase their awareness and use of PrEP.
【Key words】 Men who have sex with men; pre-exposure prophylaxis; awareness; use;
- 【文献出处】 中国艾滋病性病 ,Chinese Journal of AIDS & STD , 编辑部邮箱 ,2022年12期
- 【分类号】R512.91
- 【下载频次】46