节点文献
严重急性呼吸综合征冠状病毒2环境稳定性的研究进展
Research of severe acute respiratory syndrome coronavirus 2environmental stability:a review
【摘要】 2019冠状病毒病疫情席卷全球,其病原体严重急性呼吸综合征冠状病毒2(severe acute respiratory syndrome coronavirus 2,SARS-CoV-2)主要通过呼吸道飞沫以及密切接触(直接或间接接触)传播。接触病毒污染物体导致感染的风险也受到了广泛关注。本文对SARS-CoV-2在环境中稳定性的相关研究进行了综述。对SARS-CoV-2不同变异毒株的环境稳定性研究发现,在室温和常规湿度条件下,不同毒株在环境中的存活时间均与病毒滴度有关,低滴度(<104.0 TCID50)病毒可在不同材料表面存活1~3d,高滴度(>105.0TCID50)病毒可存活3~7d。各种毒株在低温条件下均更加稳定。此外,研究未发现不同毒株对消毒剂的敏感性存在差异,醇基消毒剂、含氯消毒剂、表面活性剂等均能有效灭活SARS-CoV-2的不同变异株。当面临可能被病毒污染的环境时,应注意做好个人防护和手卫生,及时对环境表面进行消毒灭菌,以降低感染的风险。
【Abstract】 Coronavirus disease 2019 (COVID-19)has spread all over the world.Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is mainly transmitted through respiratory droplets and close contact(directly or indirectly contact).The risk of infection by contacting fomite contaminated with the virus has attracted attention.This paper reviews the researches on the stability of SARS-COV-2in the environment.Studies on the environmental stability of different variants and strains of SRAS-CoV-2find that,the survival time of virus depends on viral titer under the condition of room temperature and conventional humidity.Virus with low titer(<104.0 TCID50)can survive for 1to 3days on different surfaces,but virus with high titer(>105.0 TCID50)can survive for 3to 7days.Variants of SARS-COV-2are more stable at low temperature.In addition,variants of SARS-CoV-2have the same sensitivity to disinfectants,and can be inactivated effectively by alcohols,chlorinated disinfectants and surfactants.When ones face an environment which may be contaminated by the virus,it is necessary to pay attention to personal protection,hand hygiene,as well as disinfection timely to reduce the infection risk.
【Key words】 Severe acute respiratory syndrome coronavirus 2; Virus survival; Disinfection; Prevention and control of COVID-19;
- 【文献出处】 微生物与感染 ,Journal of Microbes and Infections , 编辑部邮箱 ,2022年04期
- 【分类号】R373
- 【下载频次】12