节点文献

严重急性呼吸综合征冠状病毒2环境稳定性的研究进展

Research of severe acute respiratory syndrome coronavirus 2environmental stability:a review

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【作者】 孙志平瞿涤

【Author】 SUN Zhiping;QU Di;Biosafety Level 3Laboratory & Shanghai Medical College Fudan University;Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS),and Department of Microbiology and Parasitology,School of Basic Medical Sciences,Fudan University;

【通讯作者】 瞿涤;

【机构】 复旦大学生物安全三级实验室复旦大学上海医学院基础医学院医学分子病毒学教育部/卫健委/医科院重点实验室

【摘要】 2019冠状病毒病疫情席卷全球,其病原体严重急性呼吸综合征冠状病毒2(severe acute respiratory syndrome coronavirus 2,SARS-CoV-2)主要通过呼吸道飞沫以及密切接触(直接或间接接触)传播。接触病毒污染物体导致感染的风险也受到了广泛关注。本文对SARS-CoV-2在环境中稳定性的相关研究进行了综述。对SARS-CoV-2不同变异毒株的环境稳定性研究发现,在室温和常规湿度条件下,不同毒株在环境中的存活时间均与病毒滴度有关,低滴度(<104.0 TCID50)病毒可在不同材料表面存活1~3d,高滴度(>105.0TCID50)病毒可存活3~7d。各种毒株在低温条件下均更加稳定。此外,研究未发现不同毒株对消毒剂的敏感性存在差异,醇基消毒剂、含氯消毒剂、表面活性剂等均能有效灭活SARS-CoV-2的不同变异株。当面临可能被病毒污染的环境时,应注意做好个人防护和手卫生,及时对环境表面进行消毒灭菌,以降低感染的风险。

【Abstract】 Coronavirus disease 2019 (COVID-19)has spread all over the world.Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is mainly transmitted through respiratory droplets and close contact(directly or indirectly contact).The risk of infection by contacting fomite contaminated with the virus has attracted attention.This paper reviews the researches on the stability of SARS-COV-2in the environment.Studies on the environmental stability of different variants and strains of SRAS-CoV-2find that,the survival time of virus depends on viral titer under the condition of room temperature and conventional humidity.Virus with low titer(<104.0 TCID50)can survive for 1to 3days on different surfaces,but virus with high titer(>105.0 TCID50)can survive for 3to 7days.Variants of SARS-COV-2are more stable at low temperature.In addition,variants of SARS-CoV-2have the same sensitivity to disinfectants,and can be inactivated effectively by alcohols,chlorinated disinfectants and surfactants.When ones face an environment which may be contaminated by the virus,it is necessary to pay attention to personal protection,hand hygiene,as well as disinfection timely to reduce the infection risk.

【基金】 “十三五”国家科技重大专项(2018ZX10734401);上海市科技重大专项“重大突发传染病防控关键核心技术研究”(2021.7—2026.7)
  • 【文献出处】 微生物与感染 ,Journal of Microbes and Infections , 编辑部邮箱 ,2022年04期
  • 【分类号】R373
  • 【下载频次】12
节点文献中: 

本文链接的文献网络图示:

本文的引文网络