【摘要】 目的 探讨ATP与普罗帕酮治疗儿童阵发性室上性心动过速效果对比。方法 选取三明市第一医院2013年1月—2022年5月收治的50例儿童阵发性室上性心动过速患儿作为研究对象，按患儿不同的适用证、禁忌证均分为两组（n=25）：三磷酸腺苷组、普罗帕酮组，分别给予三磷酸腺苷（adenosine triphosphate,ATP）、普罗帕酮治疗。对比两组的复律效果、复律时间、复发率、不良反应发生情况。结果 三磷酸腺苷组的室上性心动过速复律率为96.0%，普罗帕酮组为76.0%，两组复律率比较，差异有统计学意义（P <0.05）。三磷酸腺苷组的复律时间为（4.10±3.60）min，普罗帕酮组复律时间为（23.58±13.41）min，两组复律时间比较，差异有统计学意义（P <0.05）。三磷酸腺苷组的不良反应发生率为4.0%，普罗帕酮组不良反应发生率24.0%，两组不良反应发生率比较，差异有统计学意义（P <0.05）。结论 ATP、普罗帕酮治疗儿童阵发性室上性心动过速应根据患儿适用证、禁忌证合理选择适宜药物治疗，提高复律率，减少不良反应发生率，达到理想的治疗效果，减轻患儿痛苦。本研究显示，三磷酸腺苷复律率高，起效快，复律时间短，不良反应发生率低。更多还原

【Abstract】 Objective To compare the effects of adenosine triphosphate and propafenone on paroxysmal supraventricular tachycardia in children.Methods A total of 50 children with paroxysmal supraventricular tachycardia admitted in Sanming First Hospital from January 2013 to May 2022were selected as the study subjects.They were divided into two groups(n=25) according to their different indications and contraindications:adenosine tripho sphate group and propafenone group.They were treated with adenosine triphosphate and propafenone respectively,and the cardioversion effect,recurrence rate,onset speed and adverse reactions of the two groups were compared.Results The cardioversion rate of supraventricular tachycardia was 96.0% in ATP group and 76.0% in propafenone group,Two sets of comparison difference statistically significant(P <0.05).The cardioversion time of ATP group was(4.10±3.60)min,and that of propafenone group was(23.58±13.41)min,and the difference was statistically significant(P <0.05).The incidence of adverse reactions was 4.0% in the adenosine triphosphate group and 24.0% in the propafenone group,two sets of comparison difference statistically significant(P<0.05).Conclusion The treatment of paroxysmal supraventricular tachycardia in children with adenosine triphosphate and propafenone should reasonably select appropriate drugs according to the indications and contraindications,increase the rate of cardioversion,reduce the incidence of adverse reactions,achieve ideal therapeutic effect and reduce the pain of children.This study shows that adenosine triphosphate has high cardioversion rate,fast onset,short cardioversion time and low incidence of adverse reactions.更多还原