【摘要】 目的 探究胰岛素泵治疗对妊娠糖尿病（gestational diabetes mellitus,GDM）患者的治疗效果。方法 选取2021年2月—2022年2月在黑龙江省医院内分泌科住院的50例GDM患者作为研究对象，按数字表法随机分为观察组25例和对照组25例，观察组使用胰岛素泵治疗，对照组使用常规胰岛素注射治疗。比较两组患者血糖达标时间、胰岛素用量，治疗前后血糖、糖化血红蛋白（HbA1c）及患者妊娠结局。结果 观察组患者血糖达标时间短于对照组，胰岛素用量少于对照组，差异有统计学意义（P<0.05）；治疗后两组空腹血糖（FPG）、餐后2 h血糖（2 hPG）、HbA1c水平均降低，且观察组低于对照组，差异有统计学意义（P<0.05）；观察组不良妊娠结局发生率低于对照组，差异有统计学意义（P<0.05）。结论 胰岛素泵应用于GDM的治疗，能够在短时间内更好地改善血糖水平，减少胰岛素用量，不良反应发生少，妊娠结局较好。更多还原

【Abstract】 Objective To explore the therapeutic effect of insulin pump therapy in patients with gestational diabetes mellitus(GDM).Methods Fifty GDM patients hospitalized in the Department of Endocrinology, Heilongjiang Provincial Hospital from February 2021 to February 2022 were selected as the study subjects. Pregnant women were randomly divided into the observation group(25 cases) and the control group(25 cases) according to the numerical table method. The observation group was treated with insulin pump and the control group was treated with routine insulin injection. The time of blood glucose reaching the standard, insulin dosage, blood glucose, glycosylated hemoglobin(HbA1c) before and after treatment, and pregnancy outcomes were compared between the two groups.Results The time to reach the blood glucose standard in the observation group was shorter than that in the control group, and the insulin dosage was less than that in the control group, and the difference was statistically significant(P<0.05). After treatment, the levels of fasting blood glucose(FPG), 2 h postprandial blood glucose(2 hPG), and HbA1c in the two groups were decreased, and the observation group was lower than the control group, and the difference was statistically significant(P<0.05). The incidence of adverse pregnancy outcomes in the observation group was lower than that in the control group, and the difference was statistically significant(P<0.05).Conclusion The application of insulin pump in the treatment of GDM can better improve the blood glucose level in a short time, reduce the amount of insulin, reduce adverse reactions, and have a better pregnancy outcome.更多还原