【摘要】 心肌梗死后主要不良心血管事件(major adverse cardiac events,MACEs)不仅降低患者的生活质量,而且增加患者的死亡风险。及时进行血液生物学标志物检测,可预测心肌梗死后MACEs的发生,以便有针对性地开展防治。本文对预测心肌梗死后MACEs发生的血液生物学标志物的研究进展进行概述。这些血液生物学标志物不仅涵盖了心肌肌钙蛋白、脑钠肽、D-二聚体、高敏C反应蛋白以及和肽素等经典外周血标志物,而且也包含近20年来新发现的蛋白质、非编码RNA。更多还原

【Abstract】 Major adverse cardiovascular events( MACEs) after myocardial infarction( MI) decrease patients’ life quality and increase the risk of death. Timely detection of blood biomarkers can predict MACEs after MI which is beneficial for targeted prevention and treatment. This paper briefly reviews the progress in blood biomarkers to predict MACEs after MI. These blood biomarkers cover classic peripheral blood biomarkers including cardiac troponin,natriuretic peptide,D-dimer,high sensitivity C-reactive protein and copeptin,and the newly discovered protein and non-coding RNA over the past 20 years.更多还原