【摘要】 目的 ：分析探讨健脾扶正法治疗轻中度贫血肿瘤患者癌因性疲乏的临床效果。方法 ：选取2017年至2020年的轻中度贫血肿瘤患者59例作为研究对象，对照组29例，治疗组30例。所有患者均给予营养支持、心理护理等基础治疗，在此基础上对照组给予归脾丸治疗，每次8粒，每日3次；治疗组则予中医健脾扶正方药加减治疗，两组均4周为1个疗程，共2个疗程。治疗前后采用Piper疲乏评估量表（Pipers’ fatigue scale,PFS）评价患者疲乏程度，评估中医症状积分并检测血清血红蛋白与白蛋白水平。结果 ：治疗组治疗后PFS各维度评分均较治疗前降低（P <0.05），且治疗组疲乏量表情感、感知维度及总疲乏分均低于对照组（P <0.05）。两组治疗后各项中医症状积分低于同组治疗前（P <0.05），且治疗组乏力、纳差、腹胀评分低于对照组（P <0.05）。两组治疗前后血红蛋白及白蛋白水平无明显变化，两组间差异亦无统计学意义（P> 0.05）。结论 ：健脾扶正方能有效改善轻中度贫血肿瘤患者的疲乏症状，降低疲乏对肿瘤患者日常活动的影响，改善患者情绪表现、感知及认知症状，提高患者生活质量。更多还原

【Abstract】 Objective: To analyze and explore the clinical effect of Jianpifuzheng method in the treatment of cancer-related fatigue in tumor patients with mild to moderate anemia. Methods: Fifty-nine tumor patients with mild to moderate anemia from 2017to 2020 were selected as the research objects, and randomly divided into a control group with 29 cases and a treatment group with 30 case. All patients were given basic treatment such as nutritional support and psychological care, on this basis, the control group was given Guipi pills, 8 pills each time, 3 times a day; the treatment group was treated with the addition and subtraction of traditional Chinese medicine invigorating the spleen and strengthening the body. Both groups were given 4 weeks as a course of treatment, with a total of 2 courses of treatment. Before and after treatment, the Pipers’ fatigue scale(PFS) was used to evaluate the degree of fatigue,assess the TCM symptom score, and detect the levels of serum hemoglobin and albumin. Results: The scores of each dimension of PFS in the treatment group after treatment were lower than those before treatment(P<0.05), and the emotion, perception dimension and total fatigue score of fatigue scale in the treatment group were lower than those in the control group(P<0.05). The scores of TCM symptoms in the two groups after treatment were lower than those before treatment in the same group(P<0.05), and the scores of fatigue, anorexia and abdominal distension in the treatment group were lower than those in the control group(P<0.05). There was no significant change in the levels of hemoglobin and albumin before and after treatment in the two groups, and there was no significant difference between the two groups(P>0.05). Conclusion: Jianpifuzheng recipe can effectively improve the symptoms of fatigue in tumor patients with mild to moderate anemia, reduce the impact of fatigue on daily activities of tumor patients, improve their emotional performance, perception and cognitive symptoms, and improve their quality of life.更多还原