【摘要】 目的 分析FIGOⅠB-ⅡA期宫颈癌患者根治性术后下肢淋巴水肿发生率及危险因素。方法 选择行根治性术的FIGOⅠB-ⅡA期宫颈癌患者126例为研究对象。收集患者的年龄、体重、肿瘤分期等一般资料，并电话或门诊随访患者1年，统计其下肢淋巴水肿发生情况，并分析其术后下肢淋巴水肿发生的危险因素。结果 随访1年发现，126例患者中出现26例下肢淋巴水肿，发生率为20.63%,其中Ⅰ度占84.62%(22/26),Ⅱ度占15.38%(4/26),未出现Ⅲ度淋巴水肿。单因素分析发现，年龄不同、是否辅助放、化疗、术后引流时间长短、淋巴结清扫数目、是否规律运动和持续站立时间不同的患者出现下肢淋巴水肿的概率存在差异(P<0.05)。多因素Logistic回归分析发现，高龄、辅助化疗、辅助放疗、淋巴结清扫数目较多、长时间持续站立是术后出现下肢淋巴水肿的危险因素，规律运动则为保护因素(P<0.05)。结论 FIGOⅠB-ⅡA期宫颈癌患者根治性术后下肢淋巴水肿发生率较高，其中高龄、辅助放疗、辅助化疗、淋巴结清扫数目较多、长时间的持续站立是术后发生下肢淋巴水肿的独立危险因素，规律运动锻炼为保护因素，临床上可对此类患者实施针对性实施预防措施，从而降低术后出现下肢淋巴水肿的概率。更多还原

【Abstract】 Objective To analyze the incidence and risk factors of lymphedema of lower extremities in patients with FIGO ⅠB-ⅡA cervical cancer after radical operation.Methods 126 patients with FIGO ⅠB-ⅡA cervical cancer who underwent radical surgery in the gynecology ward of our hospital were selected as the research objects.The patients’ age, weight, tumor stage and other general information were collected.The patients were followed up for 1 year by telephone or outpatient service.The incidence of lymphedema of lower limbs was counted and the risk factors of postoperative lymphedema were analyzed.Results 1-year follow-up showed that 26 cases of lower extremity lymphedema occurred in 126 patients, the incidence rate was 20.63%,in which grade Ⅰ accounted for 84.62%(22/26),grade Ⅱ accounted for 15.38%(4/26),no grade Ⅲ lymphedema occurred.Univariate analysis showed that patients with different age, number of lymph node dissection, postoperative drainage time, adjuvant chemotherapy, adjuvant radiotherapy, continuous standing time and regular exercise had different probability of lower limb lymphedema(P<0.05).Multivariate logistic regression analysis showed that old age, adjuvant radiotherapy, adjuvant chemotherapy, large number of lymph node dissection and long standing were risk factors for postoperative lower extremity lymphedema, and regular exercise was the protective factor(P<0.05).Conclusion The incidence of lymphedema of lower limbs in patients with FIGO ⅠB-ⅡA cervical cancer after radical operation is relatively high.Among them, old age, adjuvant radiotherapy, adjuvant chemotherapy, large number of lymph node dissection, and long-term standing are independent risk factors of lymphedema of lower limb after radical operation.Regular exercise is the protective factor, preventive measures can be taken for such patients in clinical practice to reduce the incidence of postoperative limb lymphedema.更多还原