【摘要】 教育信息化背景下，为改进组织学与胚胎学传统教学模式的不足，河南大学组织学与胚胎学教研室以虚拟仿真实验平台为依托，构建融合多元化教学方法的线上线下混合式教学模式，并在组织学与胚胎学实验教学中实践。通过期末考试成绩数据分析和问卷调查评价教学效果。结果显示，采用线上线下混合式教学模式的班级期末考试成绩明显高于传统教学模式的班级(P<0.05)。调查问卷显示学生对混合式教学满意程度高。基于虚拟仿真实验的线上线下混合式教学模式将传统学习方式的优势和虚拟仿真实验在线学习的优势结合起来，提高学生学习兴趣和参与性，培养学生的思维能力，同时也提高教师教学水平，促使教学相长，推进信息技术与医学教育的融合，从而取得良好的教学效果。更多还原

【Abstract】 Under the background of educational informatization, in order to improve the traditional teaching mode, the authors have constructed a blended teaching mode integrating online with offline teaching based on the virtual simulation experiment platform, and applied it in the experimental teaching of histology and embryology. The results of final examination and questionnaire survey were analyzed to evaluate the teaching effect. Data analysis showed that the final assessment scores of the experimental classes were significantly higher than those of the control classes(P<0.05), and the students were satisfied with the blended teaching mode. The blended teaching mode, which combines the advantages of both traditional approach and online learning of virtual simulation experiment, has improved the students’ learning interest and participation, cultivated the students’ thinking ability, improved teachers’ teaching level, promoted the integration of information technology and medical education, and achieved better teaching results.更多还原