【摘要】 目前，被世界卫生组织界定为“全球大流行（Pandemic）”的新冠肺炎疫情已造成600多万人死亡，而肥胖、患基础性疾病及免疫低下人群对COVID-19尤为易感，病重率和病死率高。肥胖和低体力活动两者相互促进、互为因果，共同成为COVID-19感染高风险因素。作为绝佳的免疫佐剂，运动可有效对抗肥胖、2型糖尿病和心血管疾病，同时在预防感染性疾病和病后康复中起到积极作用。从肥胖对COVID-19的高易感性及全球低体力活动的现状出发，揭示不同形式运动在提升机体免疫水平中的积极作用及机制。提出：在COVID-19大流行下健康人群在做好自我防护措施的同时，可选择并保持150～300 min/周中等强度或75～150 min/周高强度的体力活动或运动，以应对肥胖，提高免疫力，降低感染风险，从而改善机体整体健康状况。更多还原

【Abstract】 At present, the COVID-19 epidemic defined by the World Health Organization as a "pandemic" has caused more than 6 million deaths, and people with obesity, underlying diseases or low immunity are particularly susceptible to COVID-19, with high morbidity and fatality rates. Obesity and physical inactivity, by interacting each other, are causal factors and also the high-risk factors for COVID-19 infection. As an excellent immune assist,physical exercise can effectively combat obesity, type 2 diabetes and cardiovascular diseases; at the same time, it plays an active role in the prevention of infectious diseases and rehabilitation after illness. Based on the high susceptibility of obesity to COVID-19 and the status quo of physical inactivity in the world, the positive effect and underlying mechanism of different forms of exercise in improving the body’s immune levels are revealed. It is proposed that healthy people, on the precondition of their good self-protection, should choose the form of physical activity and maintain 150-300 minutes of moderate-to-high-intensity exercise per week or 75-150 minutes of high intensity exercise per week to prevent obesity, improve immunity, and reduce the risk of infection, thereby improving the overall health level of the body during the COVID-19 pandemic.更多还原