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人工心脏的临床应用和研究进展

CLINICAL APPLICATION OF ARTIFICIAL HEART AND RELATED RESEARCH ADVANCES

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【作者】 颜文龙杨苏民

【Author】 YAN Wenlong;YANG Sumin;Department of Cardiovascular Surgery,The Affiliated Hospital of Qingdao University;

【通讯作者】 杨苏民;

【机构】 青岛大学附属医院心血管外科

【摘要】 近十年来,心力衰竭已成为全球范围内唯一呈现增长趋势的心血管疾病;随着人口老龄化问题越来越严重,心力衰竭的发病率也随之升高。终末期心力衰竭患者生活质量差,需多次住院治疗,且病死率高,最终需要心脏移植。然而受限于供体缺乏、移植后免疫排斥反应、移植后医疗费用高昂等因素,心脏移植技术并非适用于所有终末期心力衰竭患者。近年来人工心脏的迅速发展为终末期心力衰竭患者的治疗带来了希望,使部分患者在生存期方面获益。本文对人工心脏的发展、临床应用和研究进展进行回顾和展望。

【Abstract】 During the past ten years, heart failure has become the only cardiovascular disease showing an increasing trend worldwide, and the incidence rate of heart failure gradually increases as the population ages. Patients with end-stage heart failure tend to have poor quality of life, require multiple hospitalizations, and have high mortality rates, and finally they may require heart transplantation. However, due the limitations such as the lack of donors, immune rejection after transplantation, and high post-transplantation costs, heart transplantation is not suitable for all patients with end-stage heart failure. The rapid development of artificial hearts in recent years has brought hope for the treatment of patients with end-stage heart failure, and some patients have achieved survival benefits. This article reviews the development, clinical application, and research advances in artificial heart.

  • 【文献出处】 精准医学杂志 ,Journal of Precision Medicine , 编辑部邮箱 ,2022年06期
  • 【分类号】R318.11;R541.6
  • 【下载频次】183
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