【摘要】 目的 探讨冷超声乳化白内障吸除手术应用在硬核白内障患者治疗中的临床效果及其安全性。方法 选取2019年1月—2021年10月常熟市第二人民医院治疗的硬核白内障患者66例作为观察对象。采用系统随机盲选法分组，其中对照组33例患者接受常规超声乳化白内障吸除手术联合人工晶状体植入治疗，观察组33例患者接受冷超声乳化白内障吸除手术联合人工晶状体植入治疗。记录两组患者乳化时间、手术时间，并观察比较两组患者内皮细胞密度、角膜散光值、裸眼视力以及并发症情况。结果 观察组患者手术时间（14.07±4.92）min、术中乳化时间（20.02±4.32）s明显较对照组（20.34±6.22）min、（48.11±5.20）s更短，差异有统计学意义（P<0.05）。术前，两组患者内皮细胞密度与角膜散光值比较，差异无统计学意义（P>0.05）；术后，观察组患者内皮细胞密度（2 566.50±190.23）mm~2较对照组（2 468.10±195.32）mm~2高，角膜散光值（1.50±0.32）D较对照组（1.77±0.40）D低，差异有统计学意义（P<0.05）。术前及术后1周，观察组裸眼视力（0.13±0.03）、（0.64±0.12）D与对照组（0.14±0.01）、（0.60±0.11）D比较，差异无统计学意义（P>0.05）；而术后1 d，观察组患者裸眼视力（0.44±0.07）D高于对照组（0.33±0.05）D，差异有统计学意义（P<0.05）。观察组患者并发症发生率9.09%(3/33)较对照组30.30%(10/33)更低，差异有统计学意义（χ~2=4.694,P<0.05）。结论 冷超声乳化白内障吸除手术应用在硬核白内障患者治疗过程中，具有显著效果，值得临床大力推广与应用。更多还原

【Abstract】 Objective To investigate the clinical effect of cold ultrasonic emulsion cataract aspiration surgery application in the treatment of patients with sclerotic cataract and its safety. Methods From January 2019 to October 2021, 66 hard nucleus cataract patients treated in Changshu Second People’s Hospital were selected as the observation objects. 33 patients in the control group received conventional phacoemulsification combined with intraocular lens implantation, and 33 patients in the observation group received cold phacoemulsification combined with intraocular lens implantation. The emulsification time and operation time of the two groups were recorded, and the endothelial cell density, corneal astigmatism, naked vision and complications of the two groups were observed and compared. Results The operation time(14.07±4.92) min and emulsification time(20.02±4.32) s in the observation group were significantly shorter than those in the control group(20.34±6.22) min and(48.11±5.20) s, and the difference was statistically significant(P<0.05). Before operation, there was no statistically significant difference in endothelial cell density and corneal astigmatism between the two groups(P>0.05); after operation, the endothelial cell density(2 566.50±190.23) mm~2 in the observation group was higher than that in the control group(2 468.10±195.32) mm~2, and the corneal astigmatism(1.50±0.32) D was lower than that in the control group(1.77±0.40) D, and the difference was statistically significant(P<0.05). Before and one week after operation, there was no statistically significant difference in naked eye visual acuity between(0.13±0.03) D,(0.64±0.12) D of the observation group and(0.14±0.01) D,(0.60±0.11) D of the control group(P>0.05); on the first day after operation, the naked eye visual acuity(0.44±0.07) D in the observation group was higher than that in the control group(0.33±0.05) D, and the difference was statistically significant(P<0.05). The incidence of complications in the observation group was 9.09%(3/33) lower than that in the control group 30.30%(10/33), and the difference was statistically significant(χ~2=4.694, P<0.05). Conclusion The application of cold ultrasound emulsion cataract aspiration surgery in the treatment of patients with sclerotic cataract has significant effects and is worthy of clinical promotion and application.更多还原