【摘要】 在“以学生为中心”的核心思想和以能力为先的人才培养理念指导下，运用雨课堂、虚拟仿真实验以及慕课多种线上平台，合并线下课堂构筑线上线下混合式教学模式，结合问题导学和探究互动教学方式，丰富有机化学实验安全教学内容，创新教学方式方法，为化学实验的线上线下混合式教学提供案例参考。通过对实验安全教学的精准设计和过程实施，做到了教学课堂灵活可控，在提升学生安全意识、创新意识和科研素养及课程思政融入有机化学实验教学方面进行了探索。更多还原

【Abstract】 Under the guidance of the core idea of "student-centered" and the ability-first talent training concept, the mixed teaching model of the online and offline was performed by the use of rain classrooms, virtual simulation experiments and massive open online course, combined with offline classrooms.This mode enriches the safe teaching content of organic chemistry experiments, combining the interactive teaching method of problem-based learning.The teaching process is flexible and controllable through the precise design and process implement of safety education on experiment.The exploration is carried out in improving the students’ safety awareness, consciousness of innovation and academic literacy and integrate ideological education into organic chemistry experimental teaching.更多还原