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理气活血滴丸治疗慢性稳定性心绞痛的有效性和安全性
Efficacy and safety of Liqihuoxue dripping pills in the treatment of chronic stable angina pectoris
【摘要】 目的 观察理气活血滴丸治疗慢性稳定性心绞痛的有效性和安全性。方法 选取2016年4月在青岛大学附属医院综合内科就诊的慢性稳定性心绞痛患者204例,口服理气活血滴丸,每次10粒,每天3次,连服4周进行治疗。评估患者疗效、安全性和生活质量等指标。结果 服用4周末,心绞痛症状有效率91.66%,心电图疗效有效率65.69%,硝酸甘油停减率67.15%。共发生不良事件22例(10.78%),与药物可能有关的不良事件4例(1.96%)。治疗4周末和筛选期相比,受试者生活质量有明显提高(P均<0.01)。结论 理气活血滴丸治疗稳定性心绞痛有效可靠,安全性好,临床可继续推广应用。
【Abstract】 Objective To observe the efficacy and safety ofLiqihuoxuedripping pills in the treatment of chronic stable angina pectoris.Methods A total of 204 patients in the Affiliated Hospital of Qingdao University with chronic stable angina pectoris were enrolled, who tookLiqihuoxuedripping pills 10 capsules each time, 3 times a day for 4 weeks. Indicators such as effectiveness, safety and quality of life were regularly assessed.Results After 4 weeks′ treatment, the effective rate of the symptoms of angina pectoris were 91. 66%, the effective rate of electrocardiogram was 65. 69%, and the effective rate of nitroglycerin was 67. 15%. A total of 22 cases(10. 78%) had adverse events, and 4 cases(1. 96%) with possible drug-related adverse events. Compared with the screening period, the quality of life of the subjects was significantly improved after 4 weeks′ treatment(allP< 0. 01).Conclusion Liqihuoxuedripping pills is effective, reliable and safe in the treatment of stable angina pectoris. It can be applied clinically.
【Key words】 Chronic stable angina pectoris; Liqihuoxuedripping pills; Treatment effect;
- 【文献出处】 临床合理用药杂志 ,Chinese Journal of Clinical Rational Drug Use , 编辑部邮箱 ,2022年22期
- 【分类号】R259
- 【下载频次】85