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18F-FDG PET/CT在肾透明细胞癌病理分级与分期中的应用价值
Value of 18F-FDG PET/CT in evaluating the pathological grading and staging of clear cell renal cell carcinoma
【摘要】 目的:评估18F-FDG PET/CT在肾透明细胞癌(ccRCC)Fuhrman分级与分期中的应用价值。资料和方法 :本研究为回顾性分析,收集2016年1月—2019年12月在我院行18F-FDG PET/CT检查且病理确诊为ccRCC的患者36例,均单发;对高低分化和有无转移ccRCC的病灶最大径(MD)和最大标准摄取值(SUVmax)进行比较;评估18F-FDG PET/CT在ccRCC分级、分期中的准确性。结果:SUVmax和MD都可作为ccRCC Fuhrman分级和区分有无转移的重要参数,SUVmax 4.1和MD 37 mm可作为判别高分化ccRCC的截点,SUVmax 4.4可作为判断转移的截点。对治疗前ccRCC的分期18F-FDG PET/CT准确率为86.1%。结论:18F-FDG PET/CT在ccRCC治疗前分级和分期中有较高价值。
【Abstract】 Objective: To evaluate the value of 18F-FDG PET/CT in Fuhrman grade and staging of clear cell renal carcinoma(ccRCC). Materials and Methods: Thirty-six patients who underwent 18F-FDG PET/CT and were pathologically diagnosed as ccRCCC from January 2016 to December 2019 were retrospectively analyzed. The maximun diameter(MD) and maximum standardized uptake value(SUVmax) of the lesion obtained from 18F-FDG PET/CT examinations were analyzed, and SUVmax and MD between the high and low differentiated ccRCCs and between ccRCCs with and without metastasis were compared. Then the accuracy of the 18F-FDG PET/CT in the ccRCC grade and staging was evaluated. Results: Both SUVmax and MD could be used as important parameters for Fuhrman grade and distinguishing whether there was metastasis. SUVmax4.1 and MD 37 mm could be used as cut-off for distinguishing highly differentiated ccRCC. SUVmax 4.4 could be used as a cut-off for tumor with metastasis. The accuracy of 18F-FDG PET/CT for tumor staging before treatment of ccRCCs was 86.1%.Conclusion:18F-FDG PET/CT is of high value in Fuhrman grade and tumor staging before treatment of ccRCC.
【Key words】 Kidney Neoplasms; Adenocarcinoma,Clear Cell; Positron Emission Tomography Computed Tomography;
- 【文献出处】 中国临床医学影像杂志 ,Journal of China Clinic Medical Imaging , 编辑部邮箱 ,2022年09期
- 【分类号】R737.11;R730.44
- 【下载频次】74