【摘要】 目的 探讨活血利水法治疗膝关节镜术后早期肿痛的临床疗效。方法 按照随机数字表的方法将62例膝骨关节炎关节镜术后肿痛的患者分为对照组与治疗组，每组31例。对照组术后采用常规治疗，治疗组在对照组治疗基础上口服活血利水类中药方治疗，两组均治疗7 d。对比两组患者治疗前和治疗第3、7天后的临床疗效、视觉模拟量表评分(visual analogue scale, VAS)、Lysholm评分、膝关节肿胀值及血清中白细胞介素-6(interleukin-6,IL-6)、肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)水平。结果 治疗前两组患者VAS评分、Lysholm评分比较无统计学意义(P>0.05),治疗后VAS评分在不同时点较治疗前明显降低(P<0.05),Lysholm评分在不同时点较治疗前明显升高(P<0.05)。治疗组VAS及Lysholm评分在治疗后不同时间点与对照组比较差异具有统计学意义(P<0.05)。治疗前两组患者膝关节肿胀值比较无统计学意义(P>0.05),治疗后两组患者膝关节肿胀值不同时点较治疗前均明显降低(P<0.05),且治疗组消肿效果优于对照组(P<0.05)。治疗前两组患者血清中IL-6和TNF-α水平比较无统计学意义(P>0.05),治疗后两组患者血清中IL-6和TNF-α水平不同时点较治疗前明显降低(P<0.05),且治疗组较对照组降低明显(P<0.05)。治疗组总有效率为93.55%(29/31),对照组为74.19%(23/31),两组有效率相比差异具有统计学意义(P<0.05)。结论 活血利水法能有效改善膝骨关节炎关节镜术后肿痛症状，同时降低血清中IL-6、TNF-α水平，促进患者膝关节功能恢复。更多还原

【Abstract】 Objective To explore the clinical effect of promoting blood circulation and promoting diuresis method in the treatment of early swelling and pain after knee arthroscopy.Methods According to the method of random number table, 62 patients with swelling and pain after arthroscopy of knee osteoarthritis were divided into the control group and the treatment group, with 31 cases in each group.The control group was treated with routine treatment after operation, and the treatment group was treated with promoting blood circulation and promoting diuresis traditional Chinese medicine on the basis of the treatment of the control group.Both groups were treated for 7 days.The clinical efficacy, visual analogue scale(VAS),Lysholm score, knee swelling value, serum levels of interleukin-6(IL-6) and tumor necrosis factor-α(TNF-α) were compared between the two groups before treatment and after 3 and 7 days of treatment.Results There was no significant difference in VAS score or Lysholm score between the two groups before treatment(P>0.05).After treatment, VAS score decreased significantly at different time points compared with that before treatment(P<0.05),and Lysholm score increased significantly at different time points compared with that before treatment(P<0.05).The VAS and Lysholm scores in the treatment group were significantly different from those in the control group at different time points after treatment(P<0.05).There was no significant difference in knee swelling between the two groups before treatment(P>0.05).After treatment, the knee swelling values of the two groups were significantly lower than those before treatment(P<0.05),and the detumescence effect of the treatment group was better than that of the control group(P<0.05).There was no significant difference in serum levels of IL-6 and TNF-α between the two groups after treatment(P>0.05).After treatment, in serum levels of IL-6 and TNF-α of the two groups were significantly lower than those before treatment at different time points(P<0.05),and the level in the treatment group was significantly lower than that in the control group(P<0.05).The total effective rate of the treatment group was 93.55%(29/31) and that of the control group was 74.19%(23/31).There was significant difference between the two groups(P<0.05).Conclusion The method of promoting blood circulation and promoting diuresis can effectively improve the swelling and pain symptoms of knee osteoarthritis after arthroscopy and reduce serum levels of IL-6 and TNF-α to promote the recovery of knee function.更多还原