【摘要】 目的 分析经皮冠状动脉介入(PCI)联合经皮血栓吸除术治疗急性心肌梗死(AMI)的临床价值。方法 收集2018年6月—2020年12月收治的112例AMI,按不同治疗方法分为研究组58例与对照组54例。研究组给予PCI联合经皮血栓吸除术治疗，对照组给予PCI治疗。比较两组手术前后心肌梗死溶栓试验(TIMI)血流分级、心功能[左心室射血分数(LVEF)、左心室舒张末期内径(LVEDd)]及心肌损伤指标[肌钙蛋白I(cTnI)、肌酸激酶同工酶(CK-MB)及N末端脑钠肽前体(NT-proBNP)],并观察两组不良心血管事件发生情况。结果 术后，研究组TIMI血流分级较治疗前有所改善，且改善程度优于对照组(P<0.05)。术后，两组LVEF较术前增高，LVEDd、cTnI、CK-MB及NT-proBNP水平较术前下降，且研究组增高或下降程度优于对照组(P<0.05)。研究组不良心血管事件总发生率低于对照组(P<0.05)。结论 PCI联合经皮血栓吸除术治疗AMI效果确切，可改善心功能，减轻心肌损伤，降低心血管不良事件发生率。更多还原

【Abstract】 Objective To analyze the clinical value of percutaneous coronary intervention(PCI) combined with percutaneous thrombus aspiration in the treatment of acute myocardial infarction(AMI) patients. Methods A total of 112 cases of AMI who were treated from June 2018 to December 2020 were collected and divided into the research group(n=58) and the control group(n=54) according to different treatment methods. The research group was given PCI combined with percutaneous thrombus aspiration, and the control group was given PCI. Thrombolysis in myocardial infarction(TIMI) blood flow classification, cardiac function [left ventricular ejection fraction(LVEF), left ventricular end-diastolic diameter(LVEDd)] and myocardial injury indexes [troponin I(cTnI), creatine kinase isoenzyme(CK-MB) and N-terminal precursor brain natriuretic peptide(NT-proBNP)] were compared between the two groups before and after surgery, and the occurrence of adverse cardiovascular events in the two groups was observed. Results After operation, the TIMI blood flow classification in the research group was improved compared with that before treatment, and the degree of improvement was better than that in the control group(P<0.05). After operation, the levels of LVEF in the two groups were higher than those before operation, while the levels of LVEDd, cTnI, CK-MB and NT-proBNP were lower than those before operation; the increase or decrease was better in the research group than in the control group(P<0.05). The total incidence of adverse cardiovascular events in the research group was significantly lower than that in the control group(P<0.05). Conclusion PCI combined with percutaneous thrombus aspiration has a definite effect in the treatment of AMI patients. It can improve the patient’s cardiac function, reduce myocardial damage, and reduce the incidence of cardiovascular adverse events.更多还原