【摘要】 具有高度特异性和稳定性的牙周生物标志物可辅助临床对牙周病分期分级进行更好划分。活化型基质金属蛋白酶-8(aMMP-8)可降解细胞外基质及基底膜，其异常表现与牙周炎的发生发展有着密切联系。本文就aMMP-8在牙周炎中的表达作一综述，旨在探讨aMMP-8成为牙周炎生物标志物的可行性。更多还原

【Abstract】 Periodontal biomarkers with high specificity and stability can contribute to classifying periodontal diseases by different stages and grades in clinic. Activated matrix metalloproteinase-8(aMMP-8) can degrade extracellular matrix and basal lamina. Abnormal expression of aMMP-8 is closely related to the initiation and development of periodontitis. In this paper, we reviewed the expression of aMMP-8 in periodontitis, aiming to explore feasibility of aMMP-8 as a biomarker of periodontitis.更多还原