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产单核细胞李斯特菌致孕晚期孕妇血流感染的临床治疗分析

Analysis of Clinical Treatment of Bloodstream Infection in Pregnant Women in the Third Trimester Caused by Listeria Monocytogenes

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【作者】 汪红; 潘斌; 孙晓红; 帅丽华; 周会祥; 欧阳良良;

【Author】 WANG Hong;PAN Bin;SUN Xiao-hong;SHUAI Li-hua;ZHOU Hui-xiang;OU-YANG Liang-liang;Clinical Laboratory, Jiujiang University Affiliated Hospital;

【通讯作者】 欧阳良良;

【机构】 九江学院附属医院检验科;

【摘要】 目的:分析产单核细胞李斯特菌致孕晚期孕妇血流感染的临床诊治过程,为该类疾病的临床救治提供参考。方法:针对临床收治的1例发热待查患者,医务人员通过实验室检查和微生物培养等手段探寻可能的致病原,并借助药敏试验判断病原菌的药敏特性,结合相关文献资料,制定出个体化的治疗方案。结果:血培养结果示产单核细胞李斯特菌阳性,提示该例患者的发热可能是由产单核细胞李斯特菌致血流感染所引起,而药敏试验结果显示该菌对青霉素、氨苄西林、红霉素、美罗培南较为敏感,临床依此调整治疗方案后,患者的发热等感染指征很快消失。结论:临床在遇到患者不明原因发热时,应积极开展病因筛查,借助各种检查手段找出致病原因,依此制定出针对性的治疗方案,促进患者的康复。

【Abstract】 Objective: To analyze the clinical diagnosis and treatment process of bloodstream infection in pregnant women in the third trimester caused by Listeria monocytogenes, and provide reference for the clinical treatment of such disease. Methods: For one clinically received patient with fever pending investigation, the medical staff searched for possible pathogens by means of laboratory test and microbial culture, etc., judged the drug susceptibility characteristics of pathogenic bacteria based on the drug susceptibility test, and developed individualized treatment regimen according to the relevant literature. Results: The results of blood culture showed that Listeria monocytogenes was positive, suggesting that the patient’s fever was possibly caused by the bloodstream infection due to Listeria monocytogenes. The drug susceptibility test results showed that the said bacteria were sensitive to penicillin, ampicillin, erythrocin and meropenem.After adjusting the clinical treatment regimen, the patient’s fever and other infection indications disappeared quickly.Conclusion: When patients with unexplained fever are found clinically, it is necessary to actively carry out etiological screening, use various examination techniques to find out the cause of disease, and develop a targeted treatment regimen,in order to promote the recovery of patients.

  • 【文献出处】 抗感染药学 ,Anti-Infection Pharmacy , 编辑部邮箱 ,2022年05期
  • 【分类号】R446.5
  • 【下载频次】36
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