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中国结直肠肿瘤经自然腔道取标本手术患者短期疗效与肿瘤学预后分析:一项5055例患者的数据库研究(英文)

Short-term and oncological outcomes of natural orifice specimen extraction surgery(NOSES) for colorectal cancer in China: a national database study of 5055 patients

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【作者】 关旭胡茜玥姜争韦烨孙东辉吴淼周海涛姚宏亮宋军民王贵玉胡军红任明扬徐庆蔡建春彭健马丹郑阳春何庆泗江波王泽军李太原燕速陈路川李铁钢熊治国池畔康亮于刚邓小东张宏谢铭韦建宝宫红彦孙学军臧卫东宋永茂赫鹏文政琦张春旭王昱晟陈瑛罡谢光伟李明章俞少俊刘海鹰蒲敏傅传刚王锡山中国经自然腔道取标本手术联盟

【Author】 Xu Guan;Xiyue Hu;Zheng Jiang;Ye Wei;Donghui Sun;Miao Wu;Haitao Zhou;Hongliang Yao;Junmin Song;Guiyu Wang;Junhong Hu;Mingyang Ren;Qing Xu;Jianchun Cai;Jian Peng;Dan Ma;Yangchun Zheng;Qingsi He;Bo Jiang;Zejun Wang;Taiyuan Li;Su Yan;Luchuan Chen;Tiegang Li;Zhiguo Xiong;Pan Chi;Liang Kang;Gang Yu;Xiaodong Deng;Hong Zhang;Ming Xie;Jianbao Wei;Hongyan Gong;Xuejun Sun;Weidong Zang;Yongmao Song;Peng He;Zhengqi Wen;Chunxu Zhang;Yusheng Wang;Yinggang Chen;Guangwei Xie;Mingzhang Li;Shaojun Yu;Haiying Liu;Min Pu;Chuangang Fu;Xishan Wang;China NOSES Alliance;Department of Colorectal Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College;Department of General Surgery, Zhongshan Hospital, Fudan University;Department of Gastrointestinal and Anal Surgery, Jilin University First Hospital;Department of Gastrointestinal Surgery, The Second People’s Hospital of Yibin;Department of Gastrointestinal Surgery, The Second Xiangya Hospital, Central South University;Department of Anorectal Surgery, First Affiliated Hospital, Zhengzhou University;Department of Colorectal Cancer Surgery, The Second Affiliated Hospital of Harbin Medical University;Department of Gastrointestinal Surgery, Affiliated Hospital of North Sichuan Medical College;Department of Gastrointestinal Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine;Department of Gastrointestinal Surgery, Zhongshan Hospital of Xiamen University;Department of General Surgery, Xiangya Hospital, Central South University;Department of General Surgery, Xinqiao Hospital, Third Military Medical University;Department of Gastrointestinal Surgery, Sichuan Cancer Hospital;Department of General Surgery, Shandong University Qilu Hospital;Department of Colorectal and Anal Surgery, Shanxi Cancer Hospital;Department of Gastrointestinal Surgery, The Affiliated Cancer Hospital of Guizhou Medical University;Department of General Surgery, The First Affiliated Hospital of Nanchang University;Department of Gastrointestinal Surgery, Qinghai University Affiliated Hospital;Department of Gastrointestinal Surgery, Fujian Medical University Cancer Hospital;Department of Gastrointestinal Surgery, Hubei Provincial Cancer Hospital;Department of Colorectal Surgery, Union Hospital, Fujian Medical University;Department of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University;Department of General Surgery, Qilu Hospital of Shandong University (Qingdao);Department of Colorectal Surgery, Shengjing Hospital of China Medical University;Department of Gastrointestinal Surgery, Affiliated Hospital of Zunyi Medical University;Department of Gastrointestinal Surgery, Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine;Department of Gastrointestinal Surgery, Yantaishan Hospital;Department of General Surgery, First Affiliated Hospital of Xi’an Jiaotong University;Department of Colorectal Surgery, The Second Affiliated Hospital of Zhejiang University School of Medicine;Department of Colorectal and Anal Surgery, The First Affiliated Hospital of Xinxiang Medical University;Department of Surgical Oncology, First Affiliated Hospital of Kunming Medical University;Department of General Surgery, Hospital No. 988 of the Chinese People’s Liberation Army Joint Support Force;Department of General Surgery, Jincheng People’s Hospital;Department of Colorectal Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College;Department of Gastrointestinal Surgery, Xuzhou Central Hospital;Department of General Surgery, Baotou Central Hospital;Department of Gastrointestinal Surgery, Affiliated Cancer Hospital and Institute of Guangzhou Medical University;Department of Gastrointestinal and Hernia Surgery, Affiliated Hospital of North Sichuan Medical College;Department of Gastrointestinal Surgery, Shanghai East Hospital, Tongji University School of Medicine;

【通讯作者】 傅传刚;王锡山;

【机构】 Department of Colorectal Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeDepartment of General Surgery, Zhongshan Hospital, Fudan UniversityDepartment of Gastrointestinal and Anal Surgery, Jilin University First HospitalDepartment of Gastrointestinal Surgery, The Second People’s Hospital of YibinDepartment of Gastrointestinal Surgery, The Second Xiangya Hospital, Central South UniversityDepartment of Anorectal Surgery, First Affiliated Hospital, Zhengzhou UniversityDepartment of Colorectal Cancer Surgery, The Second Affiliated Hospital of Harbin Medical UniversityDepartment of Gastrointestinal Surgery, Affiliated Hospital of North Sichuan Medical CollegeDepartment of Gastrointestinal Surgery, Renji Hospital, Shanghai Jiao Tong University School of MedicineDepartment of Gastrointestinal Surgery, Zhongshan Hospital of Xiamen UniversityDepartment of General Surgery, Xiangya Hospital, Central South UniversityDepartment of General Surgery, Xinqiao Hospital, Third Military Medical UniversityDepartment of Gastrointestinal Surgery, Sichuan Cancer HospitalDepartment of General Surgery, Shandong University Qilu HospitalDepartment of Colorectal and Anal Surgery, Shanxi Cancer HospitalDepartment of Gastrointestinal Surgery, The Affiliated Cancer Hospital of Guizhou Medical UniversityDepartment of General Surgery, The First Affiliated Hospital of Nanchang UniversityDepartment of Gastrointestinal Surgery, Qinghai University Affiliated HospitalDepartment of Gastrointestinal Surgery, Fujian Medical University Cancer HospitalDepartment of Gastrointestinal Surgery, Hubei Provincial Cancer HospitalDepartment of Colorectal Surgery, Union Hospital, Fujian Medical UniversityDepartment of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen UniversityDepartment of General Surgery, Qilu Hospital of Shandong University (Qingdao)Department of Colorectal Surgery, Shengjing Hospital of China Medical UniversityDepartment of Gastrointestinal Surgery, Affiliated Hospital of Zunyi Medical UniversityDepartment of Gastrointestinal Surgery, Ruikang Hospital Affiliated to Guangxi University of Chinese MedicineDepartment of Gastrointestinal Surgery, Yantaishan HospitalDepartment of General Surgery, First Affiliated Hospital of Xi’an Jiaotong UniversityDepartment of Colorectal Surgery, The Second Affiliated Hospital of Zhejiang University School of MedicineDepartment of Colorectal and Anal Surgery, The First Affiliated Hospital of Xinxiang Medical UniversityDepartment of Surgical Oncology, First Affiliated Hospital of Kunming Medical UniversityDepartment of General Surgery, Hospital No. 988 of the Chinese People’s Liberation Army Joint Support ForceDepartment of General Surgery, Jincheng People’s HospitalDepartment of Colorectal Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeDepartment of Gastrointestinal Surgery, Xuzhou Central HospitalDepartment of General Surgery, Baotou Central HospitalDepartment of Gastrointestinal Surgery, Affiliated Cancer Hospital and Institute of Guangzhou Medical UniversityDepartment of Gastrointestinal and Hernia Surgery, Affiliated Hospital of North Sichuan Medical CollegeDepartment of Gastrointestinal Surgery, Shanghai East Hospital, Tongji University School of Medicine

【摘要】 经自然腔道取标本手术(NOSES)通过无切口理念与常规手术器械的结合,表现出极佳的微创效果,并带给患者全新的就医感受.目前,尽管NOSES已广泛用于结直肠肿瘤治疗,大量研究也表明相比常规腹腔镜手术, NOSES具有恢复快、创伤小、疼痛轻等优势,但绝大多数研究均为小样本、单中心回顾性研究.本研究旨在通过分析我国5055例结直肠肿瘤NOSES患者数据,进一步探讨NOSES的短期疗效与预后.研究对象中,经直肠NOSES占整体比例的90.3%,经阴道NOSES占9.7%. NOSES术后短期并发症发生率为14.1%,吻合口瘘发生率为4.9%,腹盆腔感染率为1.9%.患者3年总生存率为93.2%,无病生存率为82.2%,局部复发率为3.6%.研究结果提示NOSES具有较好的安全性与可行性,为其应用于结直肠肿瘤治疗提供了证据.

【基金】 supported by the Beijing Municipal Science & Technology Commission (D171100002617004)
  • 【文献出处】 Science Bulletin ,科学通报(英文版) , 编辑部邮箱 ,2022年13期
  • 【分类号】R735.34
  • 【被引频次】4
  • 【下载频次】101
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