【摘要】 为了提高血管支架对血管内膜变形的匹配度和降低内膜增生概率，将血管支架设计为六韧带手性蜂窝结构，探究血管支架植入后的力学特性及在血液流动过程中壁面切应力情况。通过SolidWorks建立血管-血液-支架三维模型，基于双向流固耦合法，在Ansys Workbench中对不同壁厚的血管支架进行力学特性分析。研究表明：这种六韧带手性蜂窝结构血管支架在血流作用下，结构受到压力时，使刚性节点受力旋转，切向韧带收缩，支架整体在轴向和径向上同时收缩，整体体积减小，使支架在植入运输过程中避免对血管生物组织造成损伤，植入后轴向与径向同时扩张，利于血管支架定位；适当减小血管支架壁厚可以有效地降低壁面低剪切应力区域面积，减小内膜增生概率。更多还原

【Abstract】 In order to improve the matching degree of vascular stent to intima deformation and reduce the probability of intima hyperplasia, the vascular stent was designed as a ligament of hexachiral honeycomb structure to explore the mechanical properties of the vascular stent after implantation and the wall shear stress during blood flow. The three-dimensional model of vascular-blood-scaffold was established by SolidWorks. Based on the bidirectional fluid-solid coupling method, the mechanical properties of six-ligament chiral honeycomb vascular scaffolds with different wall thicknesses were analyzed in Ansys Workbench. Research shows that: the ligament of hexachiral honeycomb stent in the role of blood flow, structure stress, make rigid node stress rotation, tangential shrinkage, ligament scaffold on the axial and radial shrinkage at the same time, the whole overall volume decreases, and make the stents in biological tissue implant in the process of transportation to avoid blood vessels damage, implanted rear axle to and radial expansion at the same time. It is beneficial for stent positioning. Appropriately reducing the wall thickness of the stent can effectively reduce the area of the wall with low shear stress and reduce the probability of intimal hyperplasia.更多还原