【摘要】 报道了1例利奈唑胺引起血小板减少的病例，介绍了利奈唑胺诱导血小板减少症的发生机制、危险因素及防治措施.根据不良反应关联性评价分析，该患者出现血小板减少很可能与其使用利奈唑胺相关.目前，利奈唑胺诱导血小板减少症的发生机制尚不明确，长疗程用药、肾功能不全、基线时血小板计数低是利奈唑胺诱导血小板减少症的独立危险因素.临床药师应当加强药学监护，提高早期防范意识，避免药物不良反应发生.更多还原

【Abstract】 This paper reports a case of linezolid induced thrombocytopenia, and introduces the mechanism, risk factors, prevention and treatment.According to the analysis of adverse reaction correlation evaluation, this case of thrombocytopenia is probably related to the use of linezolid.At present, the mechanism of linezolid induced thrombocytopenia is still unclear.Long-term medication, renal dysfunction, and low platelet count at baseline are independent risk factors.Clinical pharmacists should strengthen pharmaceutical care, improve early prevention awareness, and avoid adverse drug reactions.更多还原