【摘要】 目的：对比超微血流成像、超声造影在指导高强度聚焦超声治疗子宫肌瘤作用。方法：回顾性分析2020年6月-2021年3月本院诊治的子宫肌瘤患者114例临床资料，均行高强度聚焦超声治疗，根据不同指导方式分组，对照组56例在超微血流成像引导下治疗，观察组58例在超声造影引导下治疗，对比两组术后不同时间随访时子宫及肌瘤变化，统计治疗期间并发症。结果：观察组术后3、6个月时子宫肌瘤体积(29.0±2.7 cm~3、14.2±2.0 cm~3)、子宫体积(179.4±18.6 cm~3、142.4±15.7 cm~3)均小于对照组(35.2±2.8 cm~3、19.0±2.4 cm~3,199.0±20.1 cm~3、156.6±10.5 cm~3),术6个月消融率(85.4±4.3)%、体积缩小率(54.0±3.8)%均高于对照组(71.2±3.7)%、(45.9±2.5)%,Adler分级的0级率(0)均高于对照组(1.8%),治疗有效率术后1个月(62.1%)、3个月(82.8%)、6个月(96.6%)高于对照组(42.9%、66.2%、85.7%)(均P<0.05)。结论：超声造影用于指导高强度聚焦超声治疗效果优于超微血流成像引导。更多还原

【Abstract】 Objective: To compare the role of ultramicro blood flow imaging and contrast-enhanced ultrasound for guiding the evaluation of the efficacy of high-intensity focused ultrasound for treating uterine fibroids. Methods: The clinical data of 114 patients with uterine fibroids between June 2020 and March 2021 were analyzed retrospectively. These patients were all given high-intensity focused ultrasound for treating uterine fibroids. These patients were divided into two groups according to different guidance methods of high-intensity focused ultrasound treatment, which included 56 patients in the control group were guided by ultramicro blood flow imaging, and 58 patients in the observation group were guided by contrast-enhanced ultrasound. The changes of the uterus and the uterus fibroids of the patients during different period of followed-up at were compared between the two groups. The incidence of complications of the patients during treatment was counted. Results: The volumes of uterine fibroids of the patients in the observation group in the 3 rd and the 6 th months after operation were 29.0±2.7 cm~3 and 14.2±2.0 cm~3, which were significantly less than those(35.2±2.8 cm~3 and 19.0±2.4 cm~3) of the patients in the control group. The volume of uterine of the patients in the observation group in the 3 rd and the 6 th months after operation were 179.4±18.6 cm~3 and 142.4±15.7 cm~3, which were significantly less than those(199.0±20.1 cm~3 and 156.6±10.5 cm~3) of the patients in the control group(P<0.05). The ablation rate of uterine fibroids(85.4±4.3 %) and the volume reduction rate of uterine fibroids(54.0±3.8 %) of the patients in the observation group in the 6 th months after operation were significantly higher than those(71.2±3.7 % and 45.9±2.5 %) of the patients in the control group. The rate of 0 grade of Adler grade(0) of the patients in the observation group was significantly higher than that(1.8%) of the patients in the control group. The effective rates of the patients in the observation group in 1 month, 3 months, and 6 months after operation were 62.1%,82.8%,and 96.6%,which were significantly higher than those(42.9%,66.2%,and 85.7%)of the patients in the control group(all P<0.05).Conclusion:The effectiveness of contrast-enhanced ultrasound for guiding the treatment of high-intensity focused ultrasound of uterine fibroids is better than that of ultramicro blood flow imaging.更多还原