【摘要】 目的 探析电针改善慢性精神分裂症患者记忆的疗效。方法 随机选取2021年3月—2022年3月期间兰州市第三人民医院收治的100例慢性精神分裂症患者为研究对象，采用随机数表法将其分为研究组（50例，采用电针配合常规治疗）和对照组（50例，采用常规治疗），比较两组患者的治疗效果及安全性。结果 治疗前，两组患者的阳性与阴性症状量表（PANSS）、韦氏成人智力量表第四版(WAIS-IV)、临床记忆量表、汉密顿焦虑量表（HAMA）、汉密顿抑郁量表（HAMD）、蒙特利尔认知评估量表（MoCA）评分比较，差异无统计学意义（P>0.05）；治疗后，研究组思维混乱、行为异常的阳性症状及焦虑、抑郁的阴性症状的改善时间均短于对照组，差异有统计学意义（t=16.776、22.819、74.674、42.349,P<0.05）。治疗后研究组PANSS、WAIS-IV、HAMA、HAMD评分均低于对照组，差异有统计学意义（t=19.910、4.022、63.733、21.449,P<0.05）。研究组临床记忆量表、MoCA评分均高于对照组，差异有统计学意义（t=51.166、16.751,P<0.05）。研究组不良反应发生率为6.00%(3/50)，低于对照组的30.00%(15/50)，差异有统计学意义（χ~2=9.756,P<0.05）。结论 对慢性精神分裂症患者实施电针治疗可显著改善其临床阳性、阴性症状并改善患者的记忆力及认知功能，且相较于常规药物干预，电针治疗的安全性较高。更多还原

【Abstract】 Objective To explore the effect of electroacupuncture on memory improvement in patients with chronic schizophrenia. Methods A total of 100 patients with chronic schizophrenia admitted to The Third People’s Hospital of Lanzhou City from March 2021 to March 2022 were randomly selected as the research objects. The patients were divided into study group(50 cases, electroacupuncture combined with conventional treatment) and control group(50cases, conventional treatment) by random number table method, and the therapeutic effects and safety of the two groups were compared. Results Before treatment, there was no significant difference in the scores of Positive and Negative Symptom Scale(PANSS), Wechsler Adult Intelligence Scale-Fourth Uk Edition(WAIS-IV), Clinical memory Scale, Hamilton Anxiety Scale(HAMA), Hamilton Depression Scale(HAMD) and Montreal Cognitive Assessment Scale(MoCA) between the two groups(P>0.05). After treatment, the remission time of positive symptoms such as confusion, abnormal behavior and negative symptoms such as anxiety and depression in the study group was lower than that in the control group, and the difference was statistically significant(t=16.776, 22.819, 74.674, 42.349, P<0.05). After treatmne, PANSS, WAIS-IV、HAMA and HAMD scores of the study group were lower than those of the control group, and the difference was statistically significant(t=19.910, 24.022, 63.733, 21.449, P<0.05). The score of clinical memory scale and MoCA in the study group was higher than that in the control group, and the difference was statistically significant(t=51.166, 16.751, P<0.05). The incidence of adverse reactions in the study group was 6.00%(3/50) lower than that in the control group 30.00%(15/50), and the difference was statistically significant(χ~2=9.756, P<0.05). Conclusion Electroacupuncture therapy in patients with chronic schizophrenia can significantly improve the clinical positive and negative symptoms and improve the memory and cognitive function of patients, and compared with conventional drug intervention, electroacupuncture therapy is safer.更多还原