【摘要】 在超声波辐射下，以3-甲酰基色酮，对硝基苯胺和亚磷酸酯为原料，“一锅法”合成了两种含色酮环的α-氨基膦酸酯类化合物，通过IR,¹H NMR,¹³C NMR,³¹P NMR,ESI-MS对其结构进行了测定和表征。对化合物4a进行了X射线衍射分析，O,O′-二乙基-α-对硝基苯氨基-α-（色酮-4-基）-甲基膦酸酯（4a）（CCDC:2080073）晶体属单斜晶系，C2/c空间群，晶胞参数为a=33.614 6（11）?,b=12.760 7（4）?,c=20.534 4（4）?,β=90.943（3）°,V=8 806.9（4）?³,Z=16,C₂₁H₂₇N₄O₃P,Mr=432.36,D_c=1.304g·cm^-3,μ=1.484,F（000）=361 6,μ(Cu_Kα)=1.541 84 mm^-1。更多还原

【Abstract】 An ultrasound promoted efficient,environment friendly process had been devised for the synthesis of two novel α-aminophosphonates through a one-pot three-component condensation of 3-formylchromone,p-nitroaniline and two different types dialkyl phosphate. The desired products were obtained in excellent yields and in high purity under solvent-free and catalyst-free conditions.Their structures were confirmed by IR,LC-MS and ¹ H NMR The crystal structure of compounds 4 a（ CCDC: 2080073） was also determined by single-crystal X-ray diffraction. It crystallized in monoclinic system,space group C2/c with a = 33. 614 6（ 11） ?,b =12. 760 7（ 4） ?,c = 20. 534 4（ 4） ?,β = 90. 943（ 3） °,V = 8 806. 9（ 4） ?3,Z=16,C₂₀ H₂₁ N₂ O₇ P,Mr = 432. 36,D_c= 1. 304 g·cm^-3,μ = 1. 484,F（ 000） = 3 616. 0,Cu_Kαradiation（ λ = 1. 541 84?）.更多还原