【摘要】 目的 研究TURBT治疗浸润性膀胱尿路上皮癌的疗效。方法 选取我院2013年3月至2016年3月收治的100例浸润性膀胱尿路上皮癌患者，按照随机数字表法分为观察组(50例)、对照组(50例)。予以对照组膀胱部分切除术治疗，予以观察组TURBT治疗。两组于术后均接受1年的化疗，且于术后5年进行随访，3个月/次。比较两组围术期指标，术前及术后6个月生存质量评分，及术后并发症、1、3、5年生存情况。结果 观察组膀胱冲洗时间、手术时间、术后住院时间均较对照组缩短，术中出血量较对照组降低；与术前比较，术后6个月两组生存质量评分均升高，且观察组高于对照组；观察组术后的并发症总发生率(10.00%)较对照组(32.00%)降低；与术后1年比较，术后3年两组无瘤生存率降低，术后5年两组无瘤生存率、总生存率降低(均P<0.05)。结论 TURBT治疗浸润性膀胱尿路上皮癌可有效优化患者围术期指标，降低并发症，改善生活质量，且术后1、3、5年生存率高。更多还原

【Abstract】 Objective To study the efficacy of TURBT in the treatment of invasive bladder urothelial carcinoma. Methods A total of 100 patients with invasive bladder urothelial carcinoma admitted to our hospital from March 2013 to March 2016 were selected, and were divided into the observation group(50 cases) and the control group(50 cases) according to the random number table method. The control group was treated with partial cystectomy, and the observation group was treated with TURBT. Both groups received chemotherapy for 1 year after surgery, and were followed up 5 years after surgery, 3 months each time. Compare the two groups of perioperative indicators, quality of life scores before and 6 months after surgery, and postoperative complications, 1, 3, and 5 year survival. Results The bladder irrigation time, operation time, and postoperative hospital stay in the observation group were shorter than those in the control group, and the amount of intraoperative blood loss was lower than that in the control group; Compared with preoperatively, the quality of life scores of both groups increased at 6 months after operation, and the observation group was higher than the control group; The total incidence of postoperative complications in the observation group(10.00%) was lower than that in the control group(32.00%); Compared with 1 year after operation, the tumor-free survival rate of the two groups decreased at 3 years after operation, and the tumor-free survival rate and overall survival rate of the two groups decreased at 5 years after operation(all P<0.05). Conclusion TURBT treatment of invasive bladder urothelial carcinoma can effectively optimize patients’ perioperative indicators, reduce complications, improve quality of life, and have a high 1, 3, and 5-year survival rate after surgery.更多还原