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持续性血液净化治疗糖尿病肾病急性肾衰竭合并酮症酸中毒的作用分析

Effect of Continuous Blood Purification on Diabetic Nephropathy with Acute Renal Failure Complicated by Ketoacidosis

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【作者】 王敏霞王旭徐家云

【Author】 WANG Min-xia;WANG Xu;XU Jia-yun;Department of Nephrology, the First Affiliated Hospital of Henan University of Science and Technology;

【通讯作者】 徐家云;

【机构】 河南科技大学第一附属医院肾内科

【摘要】 目的探讨持续性血液净化治疗糖尿病肾病急性肾衰竭合并酮症酸中毒的作用。方法 2018年8月至2020年7月等线以本院接收的此疾病患者为样本来源,从中随机选取70例病例,平分2组,分组方法为抽签法,对照组:间歇性血液透析治疗,试验组:持续性血液净化治疗,比较治疗效果,评估酮症酸中毒恢复情况。结果试验组治疗总有效率为97.15%,高于对照组(P<0.05);试验组治疗后二氧化碳结合力高于对照组(P<0.05);两组治疗后血尿素氮(BUN)、血肌酐(SCr)低于治疗前(P<0.05),组间对比试验组低于对照组(P<0.05)。结论对于糖尿病肾病急性肾衰竭合并酮症酸中毒患者,持续性血液净化治疗效果理想,改善患者肾脏功能,利于改善患者病情,值得推广。

【Abstract】 Objective To investigate the effect of continuous blood purification on diabetic nephropathy with acute renal failure complicated with ketoacidosis. Methods In August 2018-July 2020, acute renal failure in diabetic nephropathy treated with ketoacidosis exploration work, patients with this disease in our hospital to receive a sample source, from randomly selected cases, according to the selected order 1-70 number, divided two groups, grouping method for the draw method, one of the group named as the control group, another group as the experimental group, the former giving intermittent hemodialysis treatment, the latter to carry out the continuous blood purification treatment, compare the treatment effect, evaluation of ketoacidosis. Results The total effective rate of experimental group was 97.15%, which was higher than that of control group(P<0.05). The carbon dioxide binding ability of experimental group was higher than that of control group after treatment, P<0.05; After treatment, blood urea nitrogen(BUN) and serum creatinine(SCR) in two groups were lower than before treatment, P<0.05, and the experimental group was lower than the control group, P<0.05. Conclusion For diabetic nephropathy patients with acute renal failure complicated with ketoacidosis, continuous blood purification has ideal therapeutic effect and can improve the renal function of patients, which is conducive to improving the condition of patients, and is worthy of promotion.

  • 【文献出处】 罕少疾病杂志 ,Journal of Rare and Uncommon Diseases , 编辑部邮箱 ,2022年03期
  • 【分类号】R587.2;R692.5
  • 【下载频次】115
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