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不同中医体质儿童肺炎支原体肺炎的临床特点分析

Analysis of Clinical Characteristics of Mycoplasma Pneumoniae Pneumonia in Children with Different TCM Constitutions

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【作者】 曲晓红魏小玲孙静张赟李佳琳郭晶张华马香

【Author】 QU Xiaohong;WEI Xiaoling;SUN Jing;ZHANG Yun;LI Jialin;GUO Jing;ZHANG Hua;MA Xiang;Children’s Hospital Affiliated to Shandong University/Ji’nan Children’s Hospital;Cheeloo College of Medicine, Shandong University;

【通讯作者】 马香;

【机构】 山东大学附属儿童医院/济南市儿童医院山东大学齐鲁医学院

【摘要】 目的:探讨肺炎支原体肺炎(MPP)患儿的中医体质类型及不同体质的临床特点,为儿童肺炎支原体肺炎的防治提供理论参考依据。方法:收集来自山东大学附属儿童医院呼吸科病房住院的1~14岁肺炎支原体肺炎患儿300例,进行中医体质调查问卷,采用中华中医药学会标准《中医体质分类与判定》中的量表进行体质判定。比较不同体质MPP患儿的临床表现、炎症指标、影像学改变、住院时间。结果:300例研究对象中,平和质占49.33%(148/300),偏颇体质占50.67%(152/300),偏颇体中特禀质、气虚质、阴虚质占前3位。不同体质MPP患儿出现不同程度发热、喘息及胸腔积液发生率比较,差异有统计学意义(P<0.05),C反应蛋白(CRP)及降钙素原(PCT)炎症指标升高、肺功能检查异常、肺不张及肺实变等影像学改变、住院时间比较,差异均无统计学意义(P>0.05)。结论:不同中医体质的MPP患儿临床特点不同,痰湿质与湿热质易出现高热,特禀质易出现喘息,痰湿体质易出现胸腔积液,体质辨识对于指导病情的判断和评估具有重要意义。

【Abstract】 Objective: To explore the TCM constitution types and clinical characteristics of different constitutions in children with mycoplasma pneumoniae pneumonia(MPP), and to provide theoretical reference for the prevention and treatment of MPP in children. Methods: A total of 300 children with MPP aged 1-14 years old who were hospitalized in the respiratory ward of the Children’s Hospital Affiliated to Shandong University were collected.The TCM constitution questionnaire was used to determine the constitution by using the scale in the standard ’Classification and Determination of TCM Physique’ of the China Association of Traditional Chinese Medicine.The clinical manifestations, inflammatory markers, imaging changes and hospitalization time of MPP children with different constitutions were compared. Results: Among the 300 subjects, balance constitution accounted for49.33%(148/300), and biased constitution accounted for 50.67%(152/300). In biased constitution, the inherited special constitution, Qi-deficiency constitution and Yin-deficiency constitution accounted for the first three. There were statistically significant differences in the incidence of fever, wheezing and pleural effusion among MPP children with different constitution(P<0.05). There was no statistically significant difference in the levels of CRP and PCT inflammation indexes, abnormal pul monary function examination, atelectasis, lung consolidation and other imaging changes, and the hospital stay(P>0.05). Conclusion: The clinical characteristics of MPP children with different TCM constitutions are different. Phlegm-dampness constitution and damp-heat constitution are prone to high fever, inherited special constitution is prone to wheezing, and phlegm-dampness constitution is prone to pleural effusion. Constitution identification has great significance for guiding the judgment and evaluation of the disease.

【基金】 山东省中医药科技发展计划(2019-0571)
  • 【文献出处】 中医药导报 ,Guiding Journal of Traditional Chinese Medicine and Pharmacy , 编辑部邮箱 ,2022年11期
  • 【分类号】R272
  • 【下载频次】33
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