【摘要】 目的：观察关节康膏治疗膝骨关节炎的近期疗效。方法：将84例膝骨关节炎患者随机分为对照组与治疗组，每组42例。对照组患者予塞来昔布胶囊口服，治疗组患者予关节康膏口服，疗程均为4周。观察比较两组患者HSS评分、VAS评分、膝关节活动度、等速肌力测试指标及临床疗效。结果：对照组脱落7例，治疗组剔除3例、脱落2例。对照组总有效率为82.86%(29/35)，治疗组总有效率为86.49%(32/37)，两组比较，差异无统计学意义（P>0.05）。治疗4周后，两组患者HSS评分、膝关节活动度均较治疗前增加，差异均有统计学意义（P<0.05）；两组患者治疗后HSS评分、膝关节活动度比较，差异均无统计学意义（P>0.05）。治疗4周后，两组患者VAS评分均较治疗前降低（P<0.05），且治疗组患者治疗后VAS评分低于对照组，差异有统计学意义（P<0.05）。治疗4周后，两组患者屈肌峰力矩、伸肌峰力矩、平均功率均较治疗前升高（P<0.05），且治疗组患者治疗后伸肌峰力矩、平均功率均高于对照组（P<0.05）；两组患者治疗后屈肌峰力矩比较，差异无统计学意义（P>0.05）。结论：关节康膏治疗膝骨关节炎近期疗效明确，能改善疼痛、膝关节功能，提高肌肉功能及膝关节肌力，值得临床推广。更多还原

【Abstract】 Objective: To observe the short-term curative effect of Guanjiekang Ointment in the treatment of knee osteoarthritis. Methods: A total of 84 patients with knee osteoarthritis were randomly divided into control group and treatment group, with 42 cases in each group. The patients in the control group were given oral celecoxib capsules, and the patients in the treatment group were given oral administration of Guanjiekang Ointment,and the course of treatment was 4 weeks. The HSS score, VAS score, range of motion of the knee joint, isokinetic muscle strength test indexes and clinical efficacy were compared between the two groups. Results: The control group lost 7 cases, the treatment group rejected 3 cases and lost 2 cases. The total effective rate of the control group was 82.86%(29/35), and the total effective rate of the treatment group was 86.49%(32/37), there was no statistical significance between the two groups(P>0.05). After 4 weeks of treatment, the HSS score and the range of knee motion in the two groups were significantly higher than those before treatment(P<0.05). There were no significant differences in HSS score and knee motion between two groups after treatment(P>0.05). After 4 weeks of treatment, VAS score in both groups was lower than that before treatment(P<0.05), and VAS score in the treatment group was lower than that in the control group, the difference was statistically significant(P<0.05). After4 weeks of treatment, the flexor muscle peak torque, extensor muscle peak torque and average power of two groups were higher than those before treatment(P<0.05), and the extensor muscle peak torque and average power of the treatment group were higher than those in the control group(P<0.05). There was no significant difference in flexor muscle peak torque between two groups after treatment(P>0.05). Conclusion: Guanjiekang Ointment has definite recent efficacy in treating knee osteoarthritis, which can improve pain, knee function, muscle function and knee muscle strength, and is worthy of clinical promotion.更多还原