【摘要】 为了评价大黄素甲醚新型中兽药添加剂对土种鸡生产性能的影响，探讨其在畜禽生产中替代抗菌素应用的价值，选取2 250只31周龄产蛋种鸡，随机分为4个处理组(400、800、1 000和1 200 mg·kg^-1)、牛至油对照组和空白对照组，连续饲喂14 d，观察其健康状况，测定生产性能。结果表明，添加大黄素甲醚后4个处理组产蛋鸡死淘率显著低于空白对照组和牛至油组，且呈一定的剂量效应关系。400、1 000 mg·kg^-1组平均蛋质量显著高于空白对照组（P<0.05）。800 mg·kg^-1组的合格种蛋率显著高于空白对照组（P<0.05）。随着给药时间增加，400、800、1 000 mg·kg^-1组各时段合格种蛋率也逐渐增加，与给药前差异显著（P<0.05）。800、1 200 mg·kg^-1组产蛋率显著高于空白对照组（P<0.05）。大黄素甲醚处理组与牛至油组相比各项指标差异不显著。结果说明产蛋期饲料中添加大黄素甲醚可以提高产蛋种鸡的生产性能，降低死淘率。本研究结果为抗菌素替代提供了一种新的技术选择。更多还原

【Abstract】 In order to evaluate the effect of physcion, a new veterimary additive, on the performance of laying hens, and to assess its alternative to antibiotics in livestock and poultry industry 2 250 laying hens aged 31weeks were randomly divided into 4 physcion treatment groups(400, 800, 1 000, 1 200 mg·kg^-1), an oregano oil control group and a blank control group. They were fed with diets supplemented with physion or oregano oil or with basal diet for 14 days in a run and their daily performance and production performance were observed and determined. The results showed that all the physcion treatment groups had a significantly lower culling rate than the blank control group and the oregano oil control group, giving a dose response of physcion on the laying hens to a given extent. Moreover, the 400 mg·kg^-1 and 1 000 mg·kg^-1 physcion treatment groups had the significantly higher average egg weight than the blank control group（P<0.05）, and the 800 mg·kg^-1 physcion treatment group had a significantly higher qualified egg rate than the blank control group（P<0.05）. With prolonging administration of physion to the laying hens, the qualified egg rate was also observed to increase gradually in the 400 mg/kg, 800 mg/kg, and 1 000 mg·kg^-1 physion treatment groups, a significant difference between the laying hens prior to and after administration（P<0.05）. Compared to the blank control group, both800 mg·kg^-1 and 1 200 mg·kg^-1 physcion treatment groups had a higher egg-laying rate（P<0.05）. No statistical difference was found in various indexes between the physcion treatment groups and the oregano oil group.Based on the aforementioned evidence, physcion is a promising feed additive to enhance production performance and reduce culling rate of laying hens, and is a new alternative to antibiotics.更多还原