【摘要】 目的：探讨心脏移植患者手术完成后应用他汀类药物的临床效果及护理策略分析。方法：选取2018年4月—2019年4月郑州市第七人民医院收治的49例接受心脏移植术治疗的患者作为研究对象，并随访1年。采用随机数表法分为两组，即对照组24例行常规护理措施且未采用他汀类药物治疗；观察组25例行综合护理措施且采用他汀类药物治疗。比较两组患者的临床疗效，护理工作满意度，再次入院率、排斥反应发生率、平均胆固醇水平及住院时间、重症监护时间、机械通气时间。结果：观察组患者治疗总有效率高于对照组，差异有统计学意义（χ~2=7.122,P<0.05）；观察组患者护理工作满意度高于对照组，差异有统计学意义（χ~2=5.677,P<0.05）；两组患者排斥反应发生率、再次入院率比较，差异无统计学意义（χ~2=2.172、1.180,P>0.05），观察组患者平均胆固醇水平低于对照组，差异有统计学意义（t=10.836,P<0.05）；观察组患者住院时间、重症监护时间以及术后机械通气时间显著短于对照组，差异有统计学意义（t=2.861、4.618、2.841,P<0.05）。结论：接受心脏移植术治疗患者，在术后采用他汀类药物治疗的同时采用综合护理措施，能够提升患者的治疗效果，改善患者胆固醇水平。更多还原

【Abstract】 Objective: To explore the clinical effect and nursing strategy of using statins after heart transplantation. Methods:A total of 49 patients who received heart transplantation in the hospital from April 2018 to April 2019 were selected as the research subjects, and were followed up for 1 year. The patients were divided into two groups by random number table method, 24 patients in the control group received routine nursing measures and no statin therapy, 25 patients in the observation group received comprehensive nursing measures and received statin therapy. The clinical efficacy, nursing satisfaction, readmission rate, incidence of rejection, average cholesterol level, hospital stay, intensive care time, and mechanical ventilation time were compared between the two groups. Results: The total effective rate of patients in the observation group was higher than that in the control group, and the difference was statistically significant(χ~2=7.122, P<0.05). The nursing satisfaction of the observation group was higher than that of the control group, and the difference was statistically significant(χ~2=5.677, P<0.05). There was no statistically significant difference in the incidence of rejection and readmission rate between the two groups(χ~2=2.172, 1.180, P>0.05). The average cholesterol level in the observation group was lower than that in the control group, and the difference was statistically significant(t=10.836, P<0.05). The hospitalization time, intensive care time and postoperative mechanical ventilation time of the observation group were significantly shorter than those of the control group, and the differences were statistically significant(t=2.861, 4.618,2.841, P<0.05). Conclusion: For patients undergoing heart transplantation, taking comprehensive nursing measures in addition to postoperative statin therapy can improve the patients’ treatment effect and improve the patients’ cholesterol level.更多还原