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抗生素骨水泥技术在Wanger2~4级糖尿病足治疗中的应用研究

Application of Antibiotic Bone Cement Technology in the Treatment of Wanger 2-4 Diabetic Foot

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【作者】 沈晓震; 郑艳峰; 陈宗相; 吴青华; 郑旭欣;

【Author】 SHEN Xiaozhen;ZHENG Yanfeng;CHEN Zongxiang;Jinhua People’s Hospital;

【机构】 浙江省金华市人民医院骨一科;

【摘要】 目的:观察抗生素骨水泥技术在Wanger2~4级糖尿病足治疗中的应用效果。方法:选取我院40例Wanger2~4级糖尿病足患者,以简单随机分组法将其分为两组,各20例,对照组接受负压封闭引流(VSD)治疗,观察组于其基础上予以抗生素骨水泥技术治疗,比较两组治疗前后美国足踝医师协会(AOFAS)评分、视觉模拟疼痛(VAS)评分,观察两组治疗7d相关指标、住院时间、治疗费用及并发症情况。结果:观察组治疗3个月后AOFAS评分明显高于对照组(P<0.05),VAS评分明显低于对照组(P<0.05);观察组肉芽组织覆盖率、Ⅱ期创面修复成活率显著高于对照组(P<0.05);观察组住院时间明显短于对照组(P<0.05),伤口感染率、治疗总费用明显低于对照组(P<0.05)。结论:在Wanger2~4级糖尿病足治疗中采取抗生素骨水泥技术,可有效促进踝-后足功能及疼痛恢复,缩短康复进程,减小治疗费用。

【Abstract】 Objective:To observe application effect of antibiotic bone cement technology in the treatment of Wanger 2-4 diabetic foot(DF).Methods:A total of 40 patients with Wanger 2~4 DF were selected and randomly divided into 2 groups by random number table method,with 20 cases in each. The control group was treated with vacuum sealing drainage(VSD). On this basis,the experimental group was treated with antibiotic bone cement. Before and after treatment,scores of American Orthopaedic Foot and Ankle Society(AOFAS)and visual analog scale(VAS)were compared between the two groups. The related indexes at 7d after treatment,hospitalization time,treatment cost and complications in the 2 groups were observed.Results:At 3months after treatment,AOFAS score in the experimental group was significantly higher,while VAS score was significantly lower,than the control group(P<0.05). The coverage rate of granulation tissue and survival rate of stage II wound repair in experimental group were significantly higher than those in control group(P<0.05).The hospitalization time in experimental group was significantly shorter than that in control group(P<0.05),and wound infection rate and total treatment cost were significantly lower than those in control group(P <0.05).Conclusion:The application of antibiotic bone cement technology in treatment of Wanger 2-4 DF can effectively promote recovery of ankle-hind foot function and pain,shorten rehabilitation process and reduce treatment cost.

【基金】 金华市科学技术局研究计划项目,(编号:2019-4-047)
  • 【分类号】R587.2
  • 【被引频次】2
  • 【下载频次】233
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