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基于数据挖掘的唐江山主任治疗慢性萎缩性胃炎的用药规律分析

Analysis of Medication Rule of Director Tang JiangShan in Treating Chronic Atrophic Gastritis Based on Data Mining

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【作者】 谢玉玲李丹刘玉凤温建英张玉琴徐伟唐江山

【Author】 XIE Yu-ling;LI Dan;LIU Yu-feng;WEN Jian-ying;ZHANG Yu-qin;XU Wei;TANG Jiang-shan;Fuzhou Hospital of Traditional Chinese Medicine Affiliated to Fujian University of Traditional Chinese Medicine;Fuzhou Hospital of Traditional Chinese Medicine;Fujian University of Traditional Chinese Medicine;

【通讯作者】 徐伟;

【机构】 福建中医药大学附属福州中医院福州市中医院福建中医药大学

【摘要】 目的 挖掘唐江山主任治疗慢性萎缩性胃炎的用药规律。方法 搜集处方,建立数据库,从证候、性味、归经、用药频次与剂量、药物间的关联性等方面探索唐江山主任治疗慢性萎缩性胃炎的用药规律。结果 共收集方剂328首,证型分布上以虚证为主;用药方面以益气健脾、活血化瘀、行气导滞、清热解毒中药为主;药物在四气分布上以寒、温为主;五味分布以苦、甘味为主,辛味次之;归经上以脾、胃、肺、肝经药物为主;主要药对6组;治疗慢性萎缩性胃炎的药物以黄芪、党参、白术、莪术、蒲公英、海螵蛸、马勃、木蝴蝶、刺猬皮、浙贝母、炙甘草为主方,临证加减。结论 唐江山主任从益气、消滞、化瘀、解毒方面入手,审慎药量,巧治慢性萎缩性胃炎。

【Abstract】 OBJECTIVE To explore the medication rule of Director Tang JiangShan in the treatment of chronic atrophic gastritis.METHODS Collect prescriptions, establish a database, and explore director Tang JiangShan′s medication rules in the treatment of chronic atrophic gastritis from the aspects of syndrome, nature and flavor, meridian, frequency and dosage of medication, and the correlation between medications.RESULTS A total of 328 prescriptions were collected, and deficiency syndrome was the main syndrome type distribution; In terms of medication, traditional Chinese medicine is mainly used to replenish qi and strengthen the spleen, activate blood circulation and remove blood stasis, guide qi stagnation, clear away heat and detoxify; In the distribution of four natures of drugs, the drugs are mainly cold and warm; The five flavors are mainly bitter and sweet, followed by pungent; The drugs of spleen, stomach, lung and liver meridians are the main ones; The main drug pairs are 6 groups; The drugs for the treatment of chronic atrophic gastritis are mainly astragalus membranaceus, codonopsis pilosula, atractylodis macrocephalae rhizoma, curcuma zedoaria, dandelion, cuttlebone, lasiosphaera calvatia, semen oroxyli, hedgehog skin, thunberg fritillary bulb and radix glycyrrhizae Preparata.CONCLUSION Director Tang JiangShan started with Supplementing Qi, eliminating stagnation, removing blood stasis and detoxification, carefully controlled the dosage and skillfully treated chronic atrophic gastritis.

【基金】 福建中医药大学2020年校管课题临床专项(项目编号:XB2020078);2020年福州市第二批科技计划项目(项目编号:2020-WS-51);福建省中医重点专科(中药临床药学)(编号:闽卫中医函[2019]262号);黄秋云全国名老中医药专家传承工作室(编号:闽卫中医药[2019]21号)
  • 【文献出处】 海峡药学 ,Strait Pharmaceutical Journal , 编辑部邮箱 ,2022年04期
  • 【分类号】R259;R249
  • 【下载频次】68
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