【摘要】 目的 了解近20年来干眼症相关生活质量研究现状、热点以及发展趋势。方法 收集Web of Science Core Collection数据库中发表于2001年1月1日至2020年12月31日的干眼症相关生活质量研究的文献，利用CiteSpace软件绘制国家和机构合作网络图谱，VOSviewer软件绘制作者、期刊合作网络图谱以及关键词共现分析图谱。结果 共纳入相关文章738篇，显示近20年来干眼症相关生活质量研究发文量稳步上升，美国(n=273,36.99%)和庆应义塾大学(n=44,5.96%)分别是发文量最多的国家和机构，且美国与日本的相关机构已建立广泛合作团体。发文量最大的期刊是《Investigative Ophthalmology&Visual Science》(n=44,5.96%)。目前干眼症相关生活质量调查、管理以及干眼症患者常见心理问题是共同的研究热点。结论 国内外干眼症相关生活质量研究发展迅速，然而关于提高生活质量的干预性研究有待进一步探索。更多还原

【Abstract】 Objective To explore the research status, hotspots, and trends of dry eye-related quality of life in the past 20 years. Methods Articles regarding dry eye-related quality of life were retrieved from the Web of Science Core Collection from Jan. 1, 2001 to Dec. 31, 2020. CiteSpace software was used to map the cooperative networks of countries and institutions. VOSviewer was used to construct cooperative networks of authors and journals, and co-occurrence networks of keywords. Results A total of 738 related articles were included. Over the past 20 years, the number of publications has steadily increased with some fluctuations. The USA(n=273, 36.99%) and Keio University(n=44,5.96%) was the most contributive country and institution, respectively. Relevant organizations in the United States and Japan have established a wide range of cooperative groups. The journal that published the largest number of publications was“Investigative Ophthalmology & Visual Science”(n=44, 5.96%). The survey, management, and psychological problems of dry eye-related quality of life are common research directions and themes. Conclusion The research on dry eye-related quality of life has developed rapidly at home and abroad. However, interventional research to improve the dry eye-related quality of life needs further exploration.更多还原