【摘要】 为探究银杏叶提取物生产柱层析废液中奎宁酸工艺的最佳参数。以吸附率和解析率为指标，采用静态吸附试验对10种大孔树脂进行筛选，并通过动态吸附试验纯化条件。结果表明D201树脂不易碎，经处理后，可反复利用，对奎宁酸有较好的吸附和解析附效果。最佳纯化工艺参数为：径高比为1:10的D201树脂，上样液pH 3～5,上样流速1 BV·h^-1,纯净水除杂水洗到无色后，5 BV 2%甲酸进行洗脱。研究为银杏叶生产柱层析废液中奎宁酸回收利用提供了技术依据。更多还原

【Abstract】 To study the optimum parameters of separation and purification of quinic acid from the column chromatography waste liquid of Ginkgo biloba extract production, 10 macroporous resins were screened by static adsorption test with adsorption and resolution rates as indicators. The purification conditions were optimized by dynamic adsorption test to determine the optimal process parameters. The results showed that D201 resin with no-fragile and re-utilize had good adsorption and desorption effects on quinic acid in the column chromatography waste liquid of Ginkgo biloba extract. The optimal purification process parameters were as follows: D201 resin with a diameter height ratio of 1:10, loading solution pH value of of 3～5, loading solution flow rate of 1 BV·h^-1. After the purified water was used to remove and wash impurity to colorless, 5 BV 2% formic acid was used for elution. The study provided a technical basis for the recovery and utilization of quinic acid from the column chromatography waste liquid in Ginkgo biloba extract production.更多还原